BNP在心衰诊断中的应用ppt课件.pptVIP

* The graph illustrates the survival rates of CHF patients with left ventricular dysfunction using BNP as an indicator of disease severity. As expected, patients with higher disease severity, as reflected by the BNP level, had a lower chance of survival over 50 months. This work by Tsutamoto inspired a great deal of BNP research. The Triage? BNP Test is indicated for use as an aid in the diagnosis of congestive heart failure. * 这是当年阜外医院刘国仗老师调查得出的一组数据 * 国内的资料调查的是北京、河北、天津及沈阳的人群 * 美国纽约心脏病协会（New York Heart Association, NYHA） 在临床的应用非常的广 * 与传统的检测方法相比，BNP检测能对HF患者进行更客观的判断及评估。 * BNP检测通过一个量化的血液学新指标来定量判断患者是否有CHF以及CHF的严重程度。著名美籍华裔教授Alan Wu说“BNP代表了心脏标志物检测的另外一个完全崭新的方向” ，“肌钙蛋白、CK-MB，和肌红蛋白是由于心脏损伤而释放的蛋白——这些标志物说明来自损伤。BNP则是另外一类，它不表示有损伤，而是说明功能补偿”。Alan Wu教授还说“这是一种急诊必须立刻进行的试验” * 在2003年，欧美都已经将BNP检测作为一种“金标准”，甚至提出“病人入院以后首先进行的不应该是X线胸片、心超等检测，而应该是先进行BNP检测” （A single, point-of-care test of BNP level done immediately upon arrival to the emergency department had more diagnostic accuracy than did the clinician with all the tools available, including history, physical examination, conventional laboratory tests, chest x-rays, and review of old records）。 * 究竟BNP是一类什么样的物质呢？它是促尿钠排泄缩氨酸家族（NPS）的一员 The Triage? BNP Test is indicated for use as an aid in the diagnosis of congestive heart failure. * Id.-No. 1 299 832 1 489 020 1 552 007 1 777 8661 777 882 Bottle 12 12 12 12 Contents Buffer 4 x 15 mLAntibody 4 x 18 mL Buffer 3 x 70 mLAntibody 3 x 84 mL Buffer 6 x 16.5 mLAntibody 6 x 20 mL Buffer 3 x 250 mLAntibody 3 x 300 mL Analyzer Roche/Hitachi 704, 717, 911/912 Roche/Hitachi 717, 911/912 Roche/Hitachi 917, Modular P Roche/Hitachi 747 Product Also required: Precinorm? RF Precipath? RF Precimat? RF Id.-No. 1 171 275 1 661 396 1 447 971 Kit Size 3 x 1 mL 3 x 1 mL 3 x 0.5 mL Stability Shelf life Reagents on board Calibration 15 months 35 days 28 days * Listed here are the three common natriuretic peptides. Structurally, the natriuretic peptides are similar. All have a 17 AA ring structur