多发性硬化认知障碍评估及其影响因素分析-神经病学专业论文.docxVIP

万方数据 万方数据 目 录 中文摘要······························································································· （1） 英文摘要······························································································· （2） 论文题目······························································································· （3） 资料与方法···························································································· （4） 结果····································································································· （6） 讨论··································································································· （7） 结论··································································································· （11） 参考文献····························································································· （11） 文献综述····························································································· （14） 参考文献····························································································· （23） 中英文缩略语表···················································································· （27） 攻读学位期间发表文章情况····································································· （28） 个人简历····························································································· （29） 致谢··································································································· （30） 1内蒙古医科大学硕士研究生学位论文（ 1 内蒙古医科大学硕士研究生学位论文（2015） 中 文 摘 要 目的 了解多发性硬化 (multiple sclerosis，MS) 患者认知功能障碍的特点及其与患者一 般资料、神经功能缺损程度、头颅磁共振成像(magnetic resonance imaging，MRI)病变表 现之间的关系。方法 对 41 例 MS 患者及 41 名健康对照组均进行蒙特利尔认知评估 (Montreal cognitive assessment, MoCA) 量 表 、 精 神 状 态 简 易 速 检 (mini-mental state examination, MMSE)量表智能测试和常规头颅 MRI 检查，采用抑郁自评量表（Self-Rating Depression Scale，SDS）和焦虑自评量表（Self-Rating Anxiety Scale，SAS）对所有入组 成员进行精神状态评估；对 41 例 MS 患者进行扩展功能障碍状态量表(Expanded disability status Scale，EDSS)检查。统计学分析采用 SPSS13.0 软件，使用均数±标准差表示所有 数据，采用独立样本 t 检验进行患者与对照的评分差异及认知功