“双C”强化治疗脆性糖尿病优越性和适时性.docVIP

“双C”强化治疗脆性糖尿病优越性和适时性 　　【摘要】 目的：探讨“双C”强化后速效胰岛素类似物联合长效胰岛素类似物治疗脆性糖尿病的临床应用效果。方法：选择笔者所在医院2009年12月-2013年1月收治的54例脆性糖尿病患者，采用随机数字表法将其分为第一、二、三组，分别在“双C”强化后的第3天、第7天和第10天进行速效胰岛素类似物联合长效胰岛素类似物的治疗，观察三组患者治疗后血糖水平以及血糖的稳定情况。结果：三组间不同时间段的血糖水平存在一定差异，其中第一组患者各个阶段血糖水平总体而言要高于第二组和第三组，且与第二组、第三组的差异有统计学意义（P0.05）。但三组经过“双C”强化治疗后，血糖水平均较治疗前降低。结论：“双C”强化7天获得血糖波动规律及胰岛素强化治疗后，有利于掌握脆性糖尿病患者血糖规律，为后期能够更加科学、更加安全进行速效胰岛素类似物联合长效胰岛素类似物的治疗提供有力的指导，且最经济，临床上具有明显的优越性。 　　【关键词】 “双C”强化； 脆性糖尿病； 胰岛素 　　中图分类号 R587.1 文献标识码 A 文章编号 1674-6805（2013）33-0006-02 　　Double C Strengthening Superiority and Timing for The Treatment of Brittle Diabetes/LI Xin-ying.//Chinese and Foreign Medical Research，2013，11（33）：6-7 　　【Abstract】 Objective：To explore the effect of clinical application of “double C” enhanced insulin aspart combined with long-acting insulin analogues in the treatment of brittle diabetes.Method：In our hospital from 2009 December to 2013 in our hospital since January and 54 brittle for the treatment of diabetes patients， randomly divided into three groups， respectively， in the “double C” after reinforcement third days， seventh days and tenth days of insulin aspart combined with long-acting insulin analogues treatment， the three groups were observed after a certain time after treatment， blood glucose level and glucose homeostasis.Result：The three groups are not in the blood glucose level differences exist， the treatment of the first group，is in the “double C” enhanced after third days of insulin aspart combined with long-acting insulin analogues of the blood glucose levels in various stages of patients overall more than second group and third group， second group， with significant difference between third groups （P0.05）. But the three groups after the “double C”enhanced after treatment than before treatment， the blood glucose level is low.Conclusion：“Double C” enhanced 7 days to obtain the blood glucose fluctuation and after intensive insulin therapy，is conducive to grasp the law of brittle diabetes blood glucose， provide powe