16 Enterobacteriaceae Austin Community 16章肠杆菌科细菌奥斯汀社区课件.pptVIP

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16 Enterobacteriaceae Austin Community 16章肠杆菌科细菌奥斯汀社区课件.ppt

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16 Enterobacteriaceae Austin Community 16章肠杆菌科细菌奥斯汀社区课件

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Proteus species (cont’d) A: exhibits characteristic “swarming” B: shows urease positive on right Morganella species Morganella morganii is only species Documented cause of UTI Isolated from other anatomical sites Urease positive Phenylalanine deaminase positive Providencia species Providencia rettgeri is pathogen of urinary tract and has caused nosocomial outbreaks Providencia stuartii can cause nosocomial outbreaks in burn units and has been isolated from urine Both are phenylalanine deaminase positive Citrobacter species Citrobacter freundii associated with nosocomial infections (UTI, pneumonias, and intraabdominal abscesses) Ferments lactose and hydrolyzes urea slowly Methyl red positive, Simmons citrate positive Resembles Salmonella sp. Salmonella Produce significant infections in humans and certain animals Infections caused by ingestion of food or water contaminated with either human or animal feces Salmonella (cont’d) Salmonella on MacConkey Salmonella (cont’d) Lactose negative Negative for indole, VP, phenylalanine deaminase, and urease Most produce H2S Do not grow in potassium cyanide Salmonella Virulence Factors Fimbriae- help in attachment Enterotoxin Anitgenic Structures O and H structures are used for serologic grouping Vi- helpful in ID of Salmonella typhi Salmonella (cont’d) Clinical Infections Acute gastroenteritis or food poisoning Source = handling pets, insufficiently cooked eggs and chicken,milk, and contaminated cooking utensils Occurs 8 to 36 hours after ingestion Symptoms include vomiting, chills, watery diarrhea and abdominal pain Requires a high microbial load for infection Self-limiting in healthy individuals (antibiotics and antidiarrheal agents may prolong symptoms) Salmonella (cont’d) Typhoid and Other Enteric Fevers Prolonged fever Bacteremia Involvement of the RE system, particularly liver, spleen, intestines, and mesentery