毕业设计（论文）-常绿苦树的化学成分研究.docVIP

目录 一、前言 1 1.1植物资源 3 1.2植物形态 4 1.3化学成分 4 1.3.1生物碱 4 1.3.2苦味素 8 1.3.3三萜类: 11 1.3.4其他成分 12 1.4 生物活性研究 13 1.4.1抗病原微生物活性 13 1.4.2cAMP磷酸酯酶抑制活性 13 1.4.3对心血管系统的作用 14 1.4.4对消化系统的作用 14 1.4.5抗肿瘤作用 14 1.4.6其他作用 14 1.4.7毒性研究: 15 二、实验部分 15 2.1仪器和材料 15 2.2植物来源 15 2.3实验方法 15 2.4结构与讨论 17 三、结果与讨论 18 四、总结和体会 21 参考文献 22 致谢 25 附录.................................................................................................................................26 文献翻译.........................................................................................................................32 常绿苦树的化学成分研究摘 要：目的：对(Picrasma javanica)进行系统的植物化学研究，以期从中发现具有潜在生物活性的单体化合物，，为进一步开发利用提。方法：采用正相硅胶、反相硅胶、Sephadex LH-20、薄层制备以及高效液相色谱（HPLC）等各种分离方法对95%乙醇提取物中进行化学成分研究，通过波谱方法(13C-NMR)对化合物进行结构鉴定。结果：分离得到了个化合物：α-tocopherolquinone(1),(2), scopoletin(3), quassin(4), phytol(5), picrasin B acetate(6), picrasidine I (7), niloticin (8)。结论：关键词：；；化学成分Studies on the Chemical Constituents of Picrasma javanica. ABSTRACT: AIM: In order to study on chemical components of Picrasma javanica BL. and find some useful bioactive secondary metabolites, we systematically investigated the chemical constituents of this plant. And to review its original biological activity of microbial resistance, anti-tumor, effects on the cardiovascular system and digestive system, have also suffered for the further development and utilization of Picrasma javanica provide reference METHORDS: Using silica gel, RP-silica gel, MCI, Sephadex LH-20, thin-layer preparation and high performance liquid chromatography (HPLC) separation and other hardships on the evergreen tree, 95% ethanol extract of the chemical constituents of by spectroscopic methods (NMR, 13C-NMR) on the structural identification. RESULTS: Eight compounds isolated from Picrasma javanica: (1), α-tocopherolquinone (2), dehydrocrenatine, (3), scopoletin (4), quassin (5), phytol (6), picrasin B acetate (7), picrasidine I, (8), niloticin .CONCLUSION: Compound 1 and 8 w