〖医学〗泌尿系统A教材-课件.ppt

* Urinary System Li Jinxin, associate professor No.1020603 Department of Histology and Embryology Objectives 1.Structure and function of each component of a nephron. 2.Ultrastructure of the filtration barrier of the renal glomerulus. 3.Components, structure and function of the juxtaglomerular complex. Urinary System Components kidney,ureters,bladder,urethra Functions: remove waste products of metabolism regulate the homeostasis secrete some bioactive factors 1.1???General structure capsule: DCT parenchyma: cortex: medullary ray cortical labyrinth renal columns medulla: renal pyramid interstitium: CT, BV, N 1. Kidney According to function, renal parenchyma is made up of numerous nephron and collecting duct. A nephron consists of two components: the renal corpuscle and the renal tubule. Each renal tubule and collecting duct is made up of numerous epithelial-line tubules termed uriniferous tubules. cortical labyrinth medullary ray cortex medulla renal lobe: one renal pyramid and its bounding cortical tissue renal lobule: renal tissue including one medullary ray and cortical tissue surround it. 1.2 Nephron The nephron is the structural and functional unit of the kidney, composed of two parts:renal corpuscle and renal tubule. There are about one to two million nephrons in each kidney. Depending on the location of the renal corpuscle ,nephrons may be classified as cortical or juxtamedullary nephron. renal corpuscle: renal glomerulus renal capsule renal tubule: proximal tubule: --convoluted portion --straight portion thin segment distal tubule: --straight portion --convoluted portion 1.2.1 renal corpuscle spherical, 200μm in diameter. two poles: vascular pole and urinary pole two parts: glomerulus renal capsule (Bowman’s capsule) renal capsule two layers capsule –formed by beginning part of ren