Agilent 1200 ELSD customer training 教材.pptVIP

Agilent ELSD Technology Pressure effect on signal June 2007 Page * What is Gain? June 2007 Page * Gain is the sensitivity: higher gain, higher signal ? Gain range : 1 to 12 ? Factor 2 between each gain ?…means that 2048 times less concentrated impurities at gain 12 gives same peak height as main peak at gain 1. What is Gain? June 2007 Page * What is Filter ? June 2007 Page * Filter is a moving average. User can choose its duration from 0, 0.5, 1, 2, 3,…10s Most important effect June 2007 Page * Most important effect is temperature - Volatility ? Degradation with temperature ? Applications : - control of non volatile: increase T° - quality control, unknown, impurities : decrease T° ELSD Value Proposition for Customers For samples w/o chromophore or fluorescence; natural products, unknowns, combinatorial chemistry libraries ... For lab managers and technicians in pharmaceutical, food and HPI industries with a need for ?universal detection“ (?show me all compounds“) Frequently used as complementary detection mode to UV and to LC/MS State of the art ELSD w/ excellent sensitivity even for semi-volatiles due to low temperature evaporation; examples for semi-volatiles: ibupofen, parabens, caffeine Service and support from single vendor Complete system operation from ChemStation, EZChrom; standalone from local keyboard June 2007 Page * SummaryMost sensitive and reliable ELSD from the industryleader Suitable for all HPLC modes incl. RRLC bysimple nebulizer change Low and high temperature evaporation Multiple control possibilities: - built-in keyboard(no Instant Pilot) - ChemStation, rev. /= B.03.02* - EZChrom Elite 3.3, Maintenance and service from one vendor June 2007 Page * * Speaker instructions: This slide set has been developed for use with external audiences. It provides an overview of Agilent Technologies, including our organization, fiscal year business results, businesses, customers, markets and culture. If you have any questions about this slid