抗生素的历史沿革及演变（英文PPT）UHCW NHS Trust Clostridium difficile rates 2002 2005PPT.ppt

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抗生素的历史沿革及演变（英文PPT）UHCW NHS Trust Clostridium difficile rates 2002 2005PPT.ppt

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抗生素的历史沿革及演变（英文PPT）UHCW NHS Trust Clostridium difficile rates 2002 2005PPT

Infection site Drug penetration e.g. Antibiotics aren’t always the answer Infection prostheses - SURGERY Bone/Soft tissue infections Some drugs like the aminoglycosides do not penetrate well Meningitis Many drugs will not penetrate CSF well IV or oral What are the considerations Depends on site of infection Oral bioavailability of the antibiotic Clear aim/end point (treatment/suppression) Licencing MAU AuditZoe Campbell F2 SHO Only those with Severe pneumonia according to CURB criteria should receive IV antibiotics 18 out of 25 patients received IV antibiotics 18 patients were classified mild/mod (? Oral antibiotics) 7 patients were classified severe (? IV antibiotics) I.V. Oral Mild/ Moderate Severe MAU Audit: IV/Oral Switch Only 2 out of 25 (8%) patients had an IV to oral switch or a review/stop date specified on initial clerking No date specified Date specified Coventry and Warwickshire Pathology Antibiotic Senior Academic Half Day Matt Rogers James Clayton Consultant Microbiologists February 2011 Objectives of the session By the end of the session you will be able to: Describe the factors that need to considered when making the choice to prescribe an antibiotic Develop an understanding of key pathogens and their susceptibility to antibiotics. You will be able to relate this to the antibiotic policy within your Trust Define what is meant by the term Antibiotic stewardship Be aware of key DOH guidelines (Clostridium difficile) that direct the development of antibiotic policies Name the antibiotics associated with Clostridium difficile State the minimum requirements of how to prescribe an antibiotic Name the key issues around route and duration of antibiotics and how this affects patients Antibiotic stewardship Ensures the optimisation of antibiotic use Only use when necessary Control who uses what Control route and duration Respond to changing needs Respond to changing Evidence/Policies Robust policing, review and stop strategies E prescribing A b