抗生素处方（英文PPT）Antibiotic PrescribingPPT.ppt

Antibiotic Prescribing;The Antibiotic Resistance Spiral;Today’s presentation;AIR Program - JHH;Restricted Anti-infectives;;“Other” – Don’t put “registrar wants it!” ;Write number on medication chart;Restricted antibiotic indications;;;Ceftriaxone;Aminoglycosides;Aminoglycosides;Dosing;Once daily dosing;Aminoglycoside action: MIC= minimal inhibitory concentration PAE= post-antibiotic effect PALE= post-antibiotic leucocyte enhancement effect;Monitoring;Dose adjustments;What if the level is sub-therapeutic??;Toxicity;Cystic Fibrosis;Vancomycin;Vancomycin;PK and PD;Dosing (See Therapeutic Guidelines: Antibiotic);Monitoring;Toxicity;Bacterial Resistance Mechanisms;mecA Encodes penicillin binding protein 2a with low affinity for beta-lactam antibiotics;Emergence of resistance in Staph. and other Gram positive bacteria;Vancomycin-resistant Enterococcal types;VRE epidemiology in Australia;CAP/HAP Surgical Prophylaxis;Surgical Prophylaxis;Any questions?