Adult hippocampal neural stem progenitor cells in vitro are vulnerable to the mycotoxin ochratoxin A英文电子书.pdfVIP
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TOXICOLOGICAL SCIENCES 98(1), 187–197 (2007) doi:10.1093/toxsci/kfm093 Advance Access publication April 21, 2007 Adult Hippocampal Neural Stem/Progenitor Cells In Vitro Are Vulnerable to the Mycotoxin Ochratoxin-A Vasyl Sava, Adriana Velasquez, Shijie Song, and Juan Sanchez-Ramos1 Department of Neurology, University of South Florida, Tampa, Florida 33612; and James Haley VA Hospital, Tampa, Florida 33612 Received March 2, 2007; accepted April 14, 2007 D 2005; Kawai et al., 2006; Lagace et al., 2006; Nacher and The common mycotoxin ochratoxin-A (OTA) accumulates in o McEwen, 2006; Rossi et al., 2006). Cranial irradiation has been w brain, causes oxidative stress, and elicits a DNA repair response n l reported to produce a deficit in neurogenesis that occurs many o that varies across brain regions and neuronal populations. Neural a
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