恶性实体肿瘤患者并发感染的病原菌分布及危险因素分析.pdfVIP

289 doi:10.3969/j.issn.1009-881X.2011.02.030 恶性实体肿瘤患者并发感染的病原菌分布及危险因素分析 摘要：目的方法 2007920106 213结果 51.848.4 27.723.91结论 关键词 中图法分类号R730.6 文献标识码A 文章编号1009-881X(2011)02-0289-03 The Characteristics of Pathogen and the Clinical Risk of Infections in Patients with Malignant Solid Tumor LIU Xi-you,CHENG Yi,ZOU Yan-mei,XIONG Hui-hua (Cancer Center,Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China) Abstract Objective To describe the characteristics of pathogens and risk factors of infection in patients with malignant solid tumor. Method 213 cases of infection with specifi c strain among patients with malignant solid tumor from September 2007 to June 2010 were retrospectively reviewed.The data of distribution of infection site,the pathogens and the clinical risk were analyzed. Result Respiratory tract(51.8) was the most frequent site of infections.In addition,Gram-negative bacterial were the leading cause of infection(48.4),followed by Gram- positive bacterial(27.7),and fungus(23.9).The cancer patients with late stage or those who received anti-cancer treatment within one month were susceptible to infection. Conclusion Gram-negative bacterial were the leading cause of infection among patients with malignant solid tumor and the infection rate of fungus increases obviously. Cancer infection management should be strengthened and the potential risk factor of infection among patients with malignant solid tumor should be controlled. Key words Malignant tumor;Infection;High risk