免疫球蛋白补体水平在儿童原发性肾病综合症患者的价值研究.docVIP

精品论文 参考文献 免疫球蛋白补体水平在儿童原发性肾病综合症患者的价值研究 1河西学院医学院 甘肃 张掖 734000 2河西学院附属张掖人民医院 甘肃 734000 【摘要】 目的:研究免疫球蛋白补体水平在儿童原发性肾病综合症患者的价值研究。方法：选取我院收治的从2013年7月至2014年12月确诊为儿童原发性肾病综合症患者40例作为观察组，另选取40例健康儿童作为对照组，将两组儿童的血清免疫球蛋白IgA、IgG、IgM、IgE含量以及补体C3、C4水平进行对比分析。结果：观察组血清中IgA含量与对照组比较差异具无统计学意义(Pgt;0.05)，IgG与IgM含量比对照组低，IgE含量比对照组高，差异均具有统计学意义(Plt;0.05)；观察组中补体C3水平明显低于对照组，差异具有统计学意义(Plt;0.05)，补体C4水平无明显差异(Pgt;0.05)。结论： 综上所述，原发性肾病综合症患儿的发病机制与体液免疫具有一定的关系，因此在治疗时应该注意调整患儿的免疫力。患儿的免疫球蛋白紊乱程度也可提前经过临床进行早期指导并确定好治疗方案，进一步提高临床效果。 【关键词】：免疫球蛋白；补体水平；儿童原发性肾病综合症；应用价值 【中图分类号】R639.2【文献标识码】A【文章编号】1001-5213(2016)09-0329-01 Study on the value of immunoglobulin complement levels in children with primary nephrotic syndrome [Abstract] Objective: To study the value of immunoglobulin complement levels in children with primary nephrotic syndrome. Methods: selected in our hospital from July 2013 to 2014 December diagnosed in children with primary nephrotic syndrome patients with 40 cases as the observation group, and other selected 40 cases of healthy children as control group, two groups of children serum immunoglobulin IgA, IgG, IgM, IgE content and complement C3, C4 level were compared and analyzed. Results: Observation of serum IgA levels and control group differences with no statistical significance (P gt; 0.05), IgG and IgM content is lower than that of control group, IgE content than in the control group compared with statistical significance (P lt; 0.05); in the observation group, the levels of complement C3 was significantly lower than that of the control group, the difference was statistically significant (P lt; 0.05) and complement C4 level of no significant difference (P gt; 0.05). Conclusion: in summary, the pathogenesis of children with primary nephrotic syndrome and humoral immunity has a certain relationship, so in the treatment should pay attention to adjust the immunity of the children. Childrens immune globulin disorder degree can also be carried out early in advance through clinical guidance and determine