垂体腺瘤论文：垂体腺瘤质地与垂体腺瘤类型、MRI信号、血供及卒中相关分析.docVIP

垂体腺瘤论文：垂体腺瘤质地与垂体腺瘤类型、MRI信号、血供及卒中相关分析 【中文摘要】本研究着重探讨垂体腺瘤质地与腺瘤类型、MRI信号、血供及卒中的相关性，为术前能较准确的评估肿瘤质地，从而选择合适的手术方式提供理论依据。方法：1.对病理诊断为垂体腺瘤的104例临床病例资料进行回顾分析研究。2.对垂体腺瘤的质地与腺瘤的类型、是否卒中、血供情况、MRI信号高低及增强情况进行卡方检验（取P＜0.05有统计学意义）及多变量Logistic回归分析,分析垂体腺瘤质地与其类型、核磁信号、血供及卒中的关系。结果：1.T2WI信号与垂体腺瘤的质地分布概率有统计学差异（P0.05），Logistic回归分析示T2WI高信号的垂体腺瘤质地软，T2WI低信号的垂体腺瘤质地韧；T1WI信号及MRI增强信号与腺瘤质地无明显相关性。2.本研究中功能性垂体腺瘤72例，质软腺瘤占46例，非功能腺瘤32例，质硬腺瘤占15例，腺瘤类型与其质地分布概率有差异，具有统计学意义（P＜0.05），Logistic回归分析示表现功能性垂体腺瘤质地相对软，非功能性腺瘤质地相对韧。3.垂体腺瘤质地分布概率与腺瘤是否卒中有差异，具有统计学意义（P＜0.05），腺瘤血供与其质地分布概率关系不具有统计学意义（P0.05），Logistic回归分析示伴卒中垂体腺瘤质地相对软，而不伴有卒中的垂体腺瘤质地相对韧。结论：垂体腺瘤质地与腺瘤类型、MRI信号及卒中密切相关。术前可以通过核磁T2WI信号、腺瘤类型及腺瘤卒中对垂体腺瘤质地进行判断，对评估手术风险及选择手术入路有重要指导意义。 【英文摘要】Object：This project focus on the relationship between texture of pituitary adenomas and tumortype,MRI signal,blood supply and stroke,in order to supply the theory that we can accurateassessment of tumor texture and select the appropriate surgical approac before surgical treatment.Methods：1. To pathology diagnosis for 104 cases of the pituitary adenoma clinical casesretrospectively analyzed research.2. To the quality of a material of pituitary adenoma with adenoma of stroke, tumortype, whether for situation, imaging and enhance signal discretion on the chi-square test (to takea statistically significant (P 0.05), and multivariable Logistic regression analysis, analysis ofpituitary adenoma with quality of a material type, MRI signal, blood supply and the stroke.Result: 1. T2WI signal and pituitary tumor quality of a material distribution probability havestatistically significant (P 0.05), Logistic regression analysis of the performance for the T2WIhigh signal of the pituitary adenoma soft, performance for T2WI low signal pituitary adenoma ofquality of a material toughness; T1WI signal and MIR enhance signal and tumor quality of amaterial is no correlation。2. The performance for the functional pituitary adenoma in 72 cases, a soft, 46 cases oftumor. The function adenoma 32 cases, qualitative hard 15 c