千斤拔属植物化学成分及药理作用的国内外研究进展-环球中医药.pdfVIP

摇1546 环球中医药2015年12月第8卷第12期摇 Global Traditional Chinese Medicine,December2015,Vol郾8,No郾12 ·综述 · 千斤拔属植物化学成分及药理作用的国内 外研究进展 乔雪摇 卓燊摇 杨子明摇 秦海洸 揖摘要铱摇 千斤拔属植物在中国一直作为民族药及民间药被广泛使用,其中有六种有确切药用 历史,在中医上此属植物具有祛风除湿、强筋壮骨、消炎止痛、舒筋活络等功效,在临床上可用于治 疗跌打损伤、腰腿痛、乳房疾病、牙痛及妇科病等。 近年来国内外学者发现此属植物中含有糖类、黄 酮类、氨基酸、甾体、生物碱、挥发油等其他化学成分,且具有类雌激素及抗雌激素样作用,以及良好 的抗炎、抗血栓、抗氧化、镇痛、对神经系统损伤的保护等生物活性。 本文通过查阅相关文献资料, 对近年来国内外所研究的千斤拔属植物的化学成分及药理作用进行综述,为此属植物进一步研究, 临床应用及新药开发提供参考。 揖关键词铱摇 千斤拔;摇 化学成分;摇 药理作用 揖中图分类号铱摇 R285摇 揖文献标识码铱摇 A摇 doi:10郾3969/ j郾issn郾1674鄄1749郾2015郾12郾038 Chemical constituents and pharmacological effects of plant Flemingia摇 QIAO Xue,ZHUO Shen , YANGZi鄄ming,et al.摇 Guangxi University of Traditional Chinese Medicine,Nanning 530001,China Corresponding author:QIN Hai鄄guang,E鄄mail:qhgwhy@126.com. 揖Abstract铱摇 The plants of Flemingia Roxb.ex Rottl have been widely used as a national medicine andfolk medicine in our country since antiquity,six of which have an exact and long history of medicinal use. In Traditional Chinese medicine,the plants of Flemingia Roxb.ex Rottl have the effects of dispelling wind and removing dampness from the body, strengthening the sinews and the bones, diminishing inflammation and relieving pain,stimulatingthecirculationof thebloodandcausingthemusclesandjoints to relax. Clinically,they canbeusedtotreattheinjuriesfromfall,fractures,contusionsandstrains,pain in thewaist and lower extremities,breast diseases,toothaches and gynecological diseases,etc. Recently, scholars both home and abroad found that the plants of Flemingia Roxb.ex Rottl contain such chemical components as sugars,flavonoids,aminoacids,steroids,alkaloids,andvolatileoils,etc. Inaddition,the plants of Flemingia Roxb.ex Rottl are anti鄄estrogenic effect and have the effects similar to xenoestrogen. Moreover,they are anti鄄inflammatory, antithrombotic, antioxidative and analgesic