早期胃癌淋巴结转移的影响因素分析.pdfVIP

• 328 • Chinese Journal of Bases and Clinics in General Surgery, Mar. 2017, Vol. 24, No.3   ·论 著· 早期胃癌淋巴结转移的影响因素分析 王银中，张艳萍，韩朝阳，付艳忠，王娟 河南理工大学第一附属医院 焦作市第二人民医院普外科一区（河南焦作  454000 ） 【摘要】   目的    探索早期胃癌淋巴结转移的影响因素。 方法     回顾性分析 2009 年 1 月至 2016 年 1 月期间 在笔者所在医院接受手术治疗的 187 例早期胃癌患者的临床资料，探索年龄、性别、肿瘤位置、肿瘤直径、肿瘤数 目、浸润深度、组织学类型、大体形态、脉管浸润及局部溃疡与淋巴结转移的关系。 结果    本组 187 例早期胃癌 患者中，检测出淋巴结转移 32 例（17.1%）。多因素 logistic 回归分析结果显示，早期胃癌患者的淋巴结转移与肿 瘤直径（OR=2.080 ，P =0.022 ）、浸润深度（OR=21.048 ，P =0.001 ）、组织学类型（OR=3.507 ，P =0.018 ）、脉管浸润 （OR=2.406，P=0.009）及局部溃疡（OR=2.738，P=0.001）均有关，肿瘤直径2 cm、浸润深度达黏膜下层、组织学类 型为未分化型、存在脉管浸润及存在局部溃疡者的淋巴结转移率较高。 结论    肿瘤直径、浸润深度、组织学类 型、脉管浸润和局部溃疡均是淋巴结转移的影响因素。 【关键词】  早期胃癌；淋巴结转移；影响因素 Clinical analysis of influence factors for lymph node metastasis of early gastric cancer patients WANG Yinzhong, ZHANG Yanping, HAN Chaoyang, FU Yanzhong, WANG Juan Department of General Surgery Area 1, The First Affiliated Hospital of Henan Polytechnic University, The Second People’s Hospital of Jiaozuo, Jiaozuo, Henan 454000, P.R.China Corresponding author: HAN Chaoyang, Email: dhcy@126.com 【Abstract 】 Objective    To explore the clinicopathological characteristics which were associated with lymph node metastases in early gastric cancer patients. Methods    Clinical data of 187 early gastric cancer patients who received surgical treatment in The Second People’s Hospital of Jiaozuo between January 2009 and January 2016, were retrospectively analyzed, and then exploring the clinicopathological characteristics which were associated with lymph node metastases in early gastric cancer, including age, gender, tumor location, diameter of tumor, number of tumor, depth of invasion, macroscopic type, histological type, venous invasion, and local ulcer. Results    In this study, 187 patients with early gastric cancer were included, and lymph node metastasis was detected in 32 patients (17.1%). Re