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核医学重点问答题-甲状腺(Nuclearmedicinekeyquestion
核医学重点问答题-甲状腺(Nuclear medicine key question answer thyroid gland)
Thyroid blood flow imaging:
1. principle: after intravenous bolus injection, the 99mTcO4- will rapidly pass through the heart and enter the thyroid arterial system and inject into the thyroid tissue. The flow and velocity of the thyroid gland reflect the function of the thyroid gland. Application of gamma camera or SPECT fast imaging agent with continuous recording of arterial blood flow and dynamic changes of thyroid uptake in the thyroid imaging, so as to obtain the blood perfusion and the function of thyroid and thyroid lesions, combined with the static image, judging the blood circulation of the thyroid lesions.
2. indications: 1. To observe the perfusion of thyroid gland during hyperthyroidism and hypothyroidism. Understand the blood flow of thyroid nodules, and help to determine the nature of thyroid nodules.
3. clinical application: evaluate the function of thyroid gland; the differential diagnosis of benign and malignant thyroid nodules.
*99mTcO4- and 131I as thyroid imaging agent?
131I is used not only for normal thyroid imaging, but also for the diagnosis of ectopic thyroid and metastatic foci of thyroid cancer. Technetium and iodine are congeners, can also be thyroid tissue uptake and concentration, but not organic, not involved in thyroid hormone synthesis, so also can make the technetium functional thyroid tissue imaging. 99mTc due to the short half-life of the salivary gland, oral cavity, nasopharynx and epithelial cells for uptake and secretion of 99mTc and developing, so 99mTc imaging specificity than 131I, but the physical property of 99mTc is much better than that of 131I, is now routinely used for thyroid imaging, when quasi detection with 131I foci should transfer to other parts the thyroid tissue or thyroid cancer.
* * how the application of nuclear medical examination method in differential diagnosis of benign and malignant thyroid nodules?
The malignant nodules and hot nodules h
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