核医学重点问答题-肾、肾上腺（Key questions and answers in nuclear medicine - kidney, adrenal gland）.docVIP

核医学重点问答题-肾、肾上腺（Key questions and answers in nuclear medicine - kidney, adrenal gland） * four, adrenal cortex imaging: 1. principle: after the introduction of radionuclide labeled cholesterol analogue into the body, it can also be absorbed by the adrenal cortex and participate in the synthesis of hormones, and the quantity and speed of its uptake are related to the function of cortex. The adrenal cortical imaging can not only display the location, shape and size of the adrenal cortex, but also display the functional status of the adrenal cortex. Dexamethasone suppression test: used to identify adrenal cortical hyperplasia and adenoma, can observe the pituitary adrenal axis function is normal. 2. method: the patient prepares: (1) block the thyroid gland, stop the medicine that influences the imaging agent and clean the intestinal tract. 3. indications: diagnosis of adrenal cortical adenoma; positioning the ectopic adrenal; the diagnosis of primary aldosteronism; diagnosis and differential diagnosis of the adrenal cortical hyperplasia; diagnosis of adrenocortical carcinoma. Contraindications: pregnant and lactating women. 4. 、 clinical application: (1) localization diagnosis of all kinds of adrenal hyperfunction diseases; localization of ectopic adrenal gland; searching for metastatic foci of adrenal cortical adenocarcinoma. * five, adrenal medullary imaging: The 1. principle: meta iodo benzyl guanidine (MIBG) compound is a kind of adrenal nerve blocker, similar to norepinephrine in the chemical structure and physiological function, can be highly selective and adrenergic receptor binding, is currently the most commonly used adrenal medullary imaging agent, 123I or 131I labeled MIBG into the body by the adrenal medulla and rich adrenergic receptors in tissue and organ uptake and development. 2. imaging agents: 131I-MIBG, 123I-MIBG Three Methods: the patients were prepared to block the thyroid gland, deactivate the drugs that affect the uptake, clean the intestinal tract