易瑞沙治疗转移性肺腺癌有效后脑膜转移（Iressa in the treatment of metastatic lung adenocarcinoma after effective meningeal metastasis）.docVIP

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易瑞沙治疗转移性肺腺癌有效后脑膜转移（Iressa in the treatment of metastatic lung adenocarcinoma after effective meningeal metastasis）.doc

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易瑞沙治疗转移性肺腺癌有效后脑膜转移（Iressa in the treatment of metastatic lung adenocarcinoma after effective meningeal metastasis）

易瑞沙治疗转移性肺腺癌有效后脑膜转移（Iressa in the treatment of metastatic lung adenocarcinoma after effective meningeal metastasis） 404 Journal of cancer progress, Vol fifth, fourth ONCOLOGY PROGRESS, July 2007, Vol 5, No 4, July 2007 Case report Iressa in the treatment of metastatic lung adenocarcinoma after effective meningeal metastasis Zhang Bao and 1 Cao Yue saddle 1 weeks 2 1 Navy General Hospital of PLA, Beijing 100037, China 2 、 Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China - Keywords lung adenocarcinoma Iressa CLC number R734 = 2/R735 = 53, document identifier A 1 clinical information The patient, male, aged 42 years, had no history of smoking. Cough, chest, back Low back pain, dyspnea in 2 months, outside the hospital diagnosed as miliary tuberculosis The nuclei were treated with antituberculous therapy for more than 3 weeks without symptomatic relief in 2005 October 24th admission. Coughing and dyspnea during hospitalization can not be level Lying, chest, back, waist, leg pain obvious, difficult to move, not touched Superficial lymph nodes, double lungs auscultation showed low respiratory sounds. Chest CT shows two Diffuse hilar space occupying lesions, double hilar and mediastinal lymph node metastasis (Fig. 1). ECT scan and CT examination showed multiple bone rotation in neck, chest and lumbar vertebrae Shift. Assay of carcinoembryonic antigen (CEA) up to 1291 5ng/ml. On October 2005, the 28 Nikkei CT guided lung biopsy The pathological diagnosis was adenocarcinoma of lung. The clinical diagnosis was advanced adenocarcinoma of lung (T4N2M1) hilar and mediastinal lymph node metastases, and two pulmonary metastases Multiple bone metastasis. In November 3, 2005 March 2nd, ~2006 underwent systemic visualization 5 cycles of therapy, for Navelbine intravenous infusion of 40mg, D1, 8, Shun Platinum, 50mg, intravenous drip, D2, 3, 4, 21 days, 1 cycles, a total of 5 cycles. At the interval of chemotherapy, the neck,