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现代液相色谱进展(三)(Advances in modern liquid chromatography (three)) 3. Liquid chromatography detector In liquid chromatography, the detector is the most vulnerable part. In the early 80s, a wide variety of detectors came out, but generally concentrated in universities and instrumentation companies. Tens of thousands of papers on detector applications. The most popular are variable wavelength detectors, and fixed wavelength detectors are widely used because they are best suited for a wide range of aromatic compounds. The refractive index detector mainly uses the space exclusion chromatography in the high polymer industry and the food and beverage industry. However, the number of papers is relatively small because the published results are rarely published in the industry. The most rapidly developing are variable open wavelength photodetectors and electrochemical detectors. Depending on the detector used, a reasonable detection of peak shape or sample purity, additional information obtained by pre column and post column derivatization techniques and other new techniques (e.g., chemical amplification or laser source usage). In addition to the detectors involved in earlier LC books, there are many reviews on the HPLC detector now, [18]. With the subsequent development, using the absorption coefficient detector sensitive capillary liquid chromatography and capillary electrophoresis, the way is discussed in light of crystal axis was improved, another way is discussed from the adsorption to electrolyte fluorescence substance is added to the mobile phase of energy conversion, improved the detection limit for continuous secondary emission. Berthod discusses the use of laser detector in LC, he discussed the need for LC detector performance, the performance of laser, and laser LC combining examples, including optical scanning, fluorescence, optical and thermal ionization ionization, refractive index, and light photometric detector. Dasgupta[19] cited 170 references to discuss post c
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