有哪些信誉好的足球投注网站the complexities of epidemiology and prevention of gastrointestinal cancers流行病学和预防胃肠道癌症的复杂性.pdfVIP
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the complexities of epidemiology and prevention of gastrointestinal cancers流行病学和预防胃肠道癌症的复杂性
Int. J. Mol. Sci. 2012, 13, 12556-12572; doi:10.3390/ijms131012556 OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Review The Complexities of Epidemiology and Prevention of Gastrointestinal Cancers Saba Haq 1, Shadan Ali 2, Ramzi Mohammad 2 and Fazlul H. Sarkar 1,2,* 1 Department of Pathology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA; E-Mail: shaq.87@ 2 Department of Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA; E-Mails: alis@ (S.A.); mohammar@ (R.M.) * Author to whom correspondence should be addressed; E-Mail: fsarkar@; Tel.: +1-313-576-8327; Fax: +1-313-576-8389. Received: 1 August 2012; in revised form: 27 August 2012 / Accepted: 27 August 2012 / Published: 1 October 2012 Abstract: Cancer epidemiology and prevention is one of the most well studied fields today. The more we can understand about the incidence and pathogenesis of this disease, the better we will be able to prevent it. Effective prevention strategies can decrease the mortality rate of cancer significantly; this is why it is important to delineate the underlying causes. It has been well recognized that genetic mutations, sporadic or hereditary, may lead to increased chance of tumorigenesis. Detecting genetic mutations can lead to the identification of hi
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