temporal associations between weather and headache analysis by empirical mode decomposition时间关系天气和头痛经验模态分解的分析.pdfVIP

Temporal Associations between Weather and Headache: Analysis by Empirical Mode Decomposition 1,2,3 4,5 3,6 7 3,8 Albert C. Yang , Jong-Ling Fuh , Norden E. Huang , Ben-Chang Shia , Chung-Kang Peng , Shuu- Jiun Wang4,5* 1 Department of Psychiatry, Chu-Tung Veterans Hospital, Hsin-Chu County, Taiwan, 2 Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, 3 Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, 4 Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 5 Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan, 6 Research Center for Adaptive Data Analysis, National Central University, Chungli, Taiwan, 7 Department of Statistics and Information Science, Fu Jen Catholic University, Taipei County, Taiwan, 8 Margret and H. A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, United States of America Abstract Background: Patients frequently report that weather changes trigger headache or worsen existing headache symptoms. Recently, the method of empirical mode decomposition (EMD) has been used to delineate temporal relationships in certain diseases, and we applied this technique to identify intrinsic weather components associated with headache incidence data derived from a large-scale epidemiological survey of headache in the Greater Taipei area. Methodology/Principal Findings: The study sample consisted of 52 randomly selected headache patients. The weather time-series parameters were detrended by the EMD method into a set