synthesis of 5-dialkyl(aryl)aminomethyl-8-hydroxyquinoline dansylates as selective fluorescent sensors for fe3+合成5-dialkyl(芳基)aminomethyl-8-hydroxyquinoline dansylates作为fe3 +选择性荧光传感器.pdfVIP

Molecules 2007, 12, 1191-1201 molecules ISSN 1420-3049 Communication Synthesis of 5-Dialkyl((aryl))aminomethyl-8-hydroxyquinoline (( )) Dansylates as Selective Fluorescent Sensors for Fe3+ Ruogu Peng, Feng Wang and Yaowu Sha* The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China; E-mail: prg@ (for Ruogu Peng) * Author to whom correspondence should be addressed. E-mail: shayw@ Received: 4 April 2007; in revised form: 21 May 2007 / Accepted: 29 May 2007 / Published: 31 May 2007 Abstract: A series of 5-dialkyl(aryl)aminomethyl-8-hydroxyquinoline dansylates were synthesized and their fluoroionophoric properties toward representative alkali ions, alkaline earth ions and transition metal ions were investigated. Among the selected ions, Fe3+ caused considerable quenching of the fluorescence, while Cr3+ caused quenching to some extent. The absence of any significant fluorescence quenching effects of the other ions examined, especially Fe2+, renders these compounds highly useful Fe3+-selective fluorescent sensors. Keywords: Fluorescent sensor, Fe3+, fluorescence quenching. Introduction A variety of metal ions are known to play vital roles in the structural, catalytic and regulatory aspects of biological systems [1a], therefore, sensitive and selective detection of these metal ions is of great importance. A large number of fluorescent sensors have been reported in re