structural investigation of biologically active phenolic compounds isolated from european tree species生物活性酚类化合物结构调查孤立的从欧洲树种.pdfVIP

Molecules 2009, 14, 4147-4158; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species Izabela Redzynia 1,†, Natasza E. Ziółkowska 1,†,#, Wiesław R. Majzner 1, Stefan Willför 2, Rainer Sjöholm 3, Patrik Eklund 3 and Grzegorz D. Bujacz 1,* 1 Institute of Technical Biochemistry, Technical University of Łódź, ul. Stefanowskiego 4/10, 90-924 Łódź, Poland; E-Mails: izared@p.lodz.pl (I.R.); nataszaz@biochem.mpg.de (N.E.Z.); wmajzner@p.lodz.pl (W.R.M.) 2 Laboratory of Organic Chemistry, Abo Akademi University, Biskopsgatan 8, FI-20500 Abo, Finland; E-Mail: swillfor@abo.fi (S.W.) 3 Laboratory of Wood and Paper Chemistry, Abo Akademi University, Porthansgatan 3, FI-20500 Abo, Finland; E-Mails: rainer.sjoholm@abo.fi (R.S.); paeklund@abo.fi (P.E.) † These authors contributed equally to this paper. # Current address: Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany. * Author to whom correspondence should be addressed; E-Mail: gdbujacz@p.lodz.pl. Received: 14 August 2009; in revised form: 2 October 2009 / Accepted: 14 October 2009 / Published: 16 October 2009 Abstract: X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction d