sodium gill potential as a tool to monitor valve closure behavior in freshwater clam corbicula fluminea in response to copper钠吉尔潜在工具监控阀关闭行为淡水蚌蚬fluminea针对铜.pdfVIP

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sodium gill potential as a tool to monitor valve closure behavior in freshwater clam corbicula fluminea in response to copper钠吉尔潜在工具监控阀关闭行为淡水蚌蚬fluminea针对铜.pdf

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sodium gill potential as a tool to monitor valve closure behavior in freshwater clam corbicula fluminea in response to copper钠吉尔潜在工具监控阀关闭行为淡水蚌蚬fluminea针对铜

Sensors 2008, 8, 5250-5269; DOI: 10.3390/s8095250 OPEN ACCESS sensors ISSN 1424-8220 /sensors Article Sodium Gill Potential as a Tool to Monitor Valve Closure Behavior in Freshwater Clam Corbicula fluminea in Response to Copper Chung-Min Liao 1,*, Chieh-Ming Lin 1, Li-John Jou 2, and Wei-Yu Chen 1 1 Department of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, Taiwan 10617, R.O. China; E-Mails: cmliao@.tw; .tw; .tw 2 Department of Biomechatronic Engineering, National Ilan University, Ilan, Taiwan 260, R.O. China; E-mail: ljjou@.tw * Author to whom correspondence should be addressed; E-mail: cmliao@.tw Received: 2 July 2008; in revised form: 14 August 2008 / Accepted: 28 August 2008 / Published: 1 September 2008 Abstract: Valve closure behavior in freshwater clam Corbicula fluminea is a biologically sensitive endpoint. The purpose of this paper was to derive an electrophysiological response model of C. fluminea to assess copper (Cu)−sodium (Na) interactions in gill membrane, whereby valve closure behavior and Cu toxicity could be monitored. The proposed model was based on the integration of Cu bioavailability, Na and Cu internalizations, and electrochemically-based gill potentials. Based on Na active transport under non-equilibrium conditions, predicted gill potential of −8.2 mV agreed reasonably well with published the measured transepithelial potential of −7 mV in C. fluminea. Our proposed framework captured the ge