有哪些信誉好的足球投注网站a mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by luciferase imaging一只老鼠从自发的骨肉瘤肺转移模型监控通过荧光素酶体内成像.pdfVIP
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a mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by luciferase imaging一只老鼠从自发的骨肉瘤肺转移模型监控通过荧光素酶体内成像
A Mouse Model of Pulmonary Metastasis from
Spontaneous Osteosarcoma Monitored In Vivo by
Luciferase Imaging
1 2 2,3 2,3 4 5
Silvia Miretti *, Ilaria Roato , Riccardo Taulli , Carola Ponzetto , Michele Cilli , Martina Olivero ,
5 6 7 8 9
Maria Flavia Di Renzo , Laura Godio , Adriana Albini , Paolo Buracco , Riccardo Ferracini
1 Department of Morphophysiology, School of Veterinary Medicine, University of Torino, Grugliasco, Turin, Italy, 2 Center for Experimental Research and Medical Studies
(CeRMS) University and A.S.O. San Giovanni Battista, Turin, Italy, 3 Department of Anatomy, Pharmacology and Forensic Medicine, University of Torino, Turin, Italy,
4 Animal Research Facility, National Institute for Cancer Research, Genoa, Italy, 5 Laboratory of Cancer Genetics of the Institute for Cancer Research and Treatment (IRCC),
University of Torino School of Medicine, Candiolo, Turin, Italy, 6 Laboratory of Pathology, Department of Pathology, A.S.O. San Giovanni Battista, Turin, Italy, 7 IRCCS
Multimedica Science and Technology Park, Milano, Italy, 8 Department of Animal Pathology, School of Veterinary Medicine, University of Torino, Grugliasco, Turin, Italy,
9 Department of Orthopaedics, A.S.O. San Giovanni Battista, Turin, Italy
Abstract
Background: Osteosarcoma (OSA) is lethal when metastatic after chemotherapy and/or surgical treatment. Thus animal
models are necessary to study the OSA metastatic spread and to validate novel therapies able to control the systemic
disease. We report the development of a syngeneic (Balb/c) murine OSA model, using a cell l
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