有哪些信誉好的足球投注网站a micro rna processing defect in rapidly progressing idiopathic pulmonary fibrosis微rna加工缺陷在特发性肺纤维化进展迅速.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
a micro rna processing defect in rapidly progressing idiopathic pulmonary fibrosis微rna加工缺陷在特发性肺纤维化进展迅速
A Micro RNA Processing Defect in Rapidly Progressing
Idiopathic Pulmonary Fibrosis
1 2 2 2 2 1
Sameer R. Oak , Lynne Murray , Athula Herath , Matthew Sleeman , Ian Anderson , Amrita D. Joshi ,
1 3 3 4 3
Ana Lucia Coelho , Kevin R. Flaherty , Galen B. Toews , Darryl Knight , Fernando J. Martinez , Cory M.
Hogaboam1*
1 Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, 2 MedImmune, Cambridge, United Kingdom,
3 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of
America, 4 Department of Anesthesiology, Pharmacology and Therapeutics, UBC James Hogg Research Centre of the Heart+Lung Institute, University of British Columbia,
Vancouver, British Columbia, Canada
Abstract
Background: Idiopathic pulmonary fibrosis exhibits differential progression from the time of diagnosis but the molecular
basis for varying progression rates is poorly understood. The aim of the present study was to ascertain whether differential
miRNA expression might provide one explanation for rapidly versus slowly progressing forms of IPF.
Methodology and Principal Findings: miRNA and mRNA were isolated from surgical lung biopsies from IPF patients with a
clinically documented rapid or slow course of disease over the first year after diagnosis. A quantitative PCR miRNA array
containing 88 of the most abundant miRNA in the human genome was used to profile lung biopsies from 9 patients with
rapidly progressing IPF, 6 patients with slowly progressing IPF
您可能关注的文档
- a comparative cradle-to-gate life cycle assessment of mid-rise office building construction alternatives laminated timber or reinforced concrete比较cradle-to-gate中高层的办公楼建筑的生命周期评估选择复合木材或混凝土.pdf
- a comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode比较反向对接策略来识别潜在的抗肿瘤药茶功能组件和绑定模式的目标.pdf
- a combinatorial code for splicing silencing uagg and gggg motifs拼接的组合代码沉默uagg段勇图案.pdf
- a comparative study of the second-order hydrophobic moments for globular proteins the consensus scale of hydrophobicity and the charmm partial atomic charges二阶的比较研究疏水力矩为球状蛋白质疏水性的共识规模和charmm部分原子的指控.pdf
- a comparative study of two folate-conjugated gold nanoparticles for cancer nanotechnology applications比较研究两个folate-conjugated金纳米粒子对癌症纳米技术的应用程序.pdf
- a comparative analysis of extra-embryonic endoderm cell lines胚外内胚层细胞系的比较分析.pdf
- a comparative study on the expression, purification and functional characterization of human adiponectin in pichia pastoris and escherichia coli表达上的比较研究,净化和功能特征的人类pastoris脂联素在毕赤酵母和大肠杆菌.pdf
- a comparative analysis of glomerulus development in the pronephros of medaka and zebrafish前肾肾小球发展的比较分析青鳉和斑马鱼.pdf
- a comparative study on three analytical methods for the determination of the neurotoxin bmaa in cyanobacteria三种分析方法进行比较研究,确定的神经毒素bmaa蓝藻.pdf
- a comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly gi coupled gpcr (c5ar) signalling比较研究的阻抗与光学label-free系统相对于标签检测主要在胃肠道耦合gpcr信号(c5ar).pdf
- a microscale modeling tool for the design and optimization of solid oxide fuel cells微尺度建模工具的设计和优化固体氧化物燃料电池.pdf
- a microscopic study of sodium cluster deposition on an insulating surface微观研究钠集群在一个绝缘表面沉积.pdf
- a microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells微流体装置暂时控制基因表达和长期在平静的将酵母细胞荧光成像.pdf
- a microtubule interactome complexes with roles in cell cycle and mitosis微管interactome复合物的角色在细胞周期和有丝分裂.pdf
- a microsatellite guided insight into the genetic status of adi, an isolated hunting-gathering tribe of northeast india微卫星制导洞察adi的遗传状况,一个孤立的支派hunting-gathering印度东北部.pdf
- a microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus分析的微流控室neuron-to-cell alpha-herpesvirus的传播和轴突运输.pdf
- a mid-cretaceous origin of sociality in xylocopine bees with only two origins of true worker castes indicates severe barriers to eusociality社会性的起源mid-cretaceous xylocopine蜜蜂只有两个真正的工人阶层的起源表明真社会性严重障碍.pdf
- a minimum of three motifs is essential for optimal binding of pseudomurein cell wall-binding domain of methanothermobacter thermautotrophicus最少的三个主题是至关重要的优化结合pseudomurein细胞wall-binding域methanothermobacter thermautotrophicus.pdf
- a mir-200b200c429-binding site polymorphism in the 3′ untranslated region of the ap-2α gene is associated with cisplatin resistancemir - 200 - b200c429结合位点多态性在ap-2α基因3u2032端非翻译区与顺铂耐药性有关.pdf
- a minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers转录因子调节的最小连接网络在人类肿瘤及其应用寻求普遍的癌症生物标记.pdf
文档评论（0）