a behavioral comparison of male and female adults with high functioning autism spectrum conditions行为的比较男性和女性成人高功能孤独症谱系的条件.pdfVIP
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a behavioral comparison of male and female adults with high functioning autism spectrum conditions行为的比较男性和女性成人高功能孤独症谱系的条件
A Behavioral Comparison of Male and Female Adults
with High Functioning Autism Spectrum Conditions
1 1 1 1 1
Meng-Chuan Lai *, Michael V. Lombardo , Greg Pasco , Amber N. V. Ruigrok , Sally J. Wheelwright ,
1 1,2 1
Susan A. Sadek , Bhismadev Chakrabarti , MRC AIMS Consortium , Simon Baron-Cohen
1 Department of Psychiatry, Autism Research Centre, University of Cambridge, Cambridge, United Kingdom, 2 School of Psychology and Clinical Language Sciences,
Centre for Integrative Neuroscience and Neurodynamics, University of Reading, Reading, United Kingdom
Abstract
Autism spectrum conditions (ASC) affect more males than females in the general population. However, within ASC it is
unclear if there are phenotypic sex differences. Testing for similarities and differences between the sexes is important not
only for clinical assessment but also has implications for theories of typical sex differences and of autism. Using cognitive
and behavioral measures, we investigated similarities and differences between the sexes in age- and IQ-matched adults with
ASC (high-functioning autism or Asperger syndrome). Of the 83 (45 males and 38 females) participants, 62 (33 males and 29
females) met Autism Diagnostic Interview-Revised (ADI-R) cut-off criteria for autism in childhood and were included in all
subsequent analyses. The severity of childhood core autism symptoms did not differ between the sexes. Males and females
also did not differ in self-reported empathy, systemizing, anxiety, depression, and obsessive-compulsive traits/symptoms or
mentalizing performance. Howev
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