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异搏定即维拉帕米(Verapamil, Vera Pammy)
异搏定即维拉帕米(Verapamil, Vera Pammy) Verapamil, Vera Pammy Vera Pammy, a narceine derivative, in 1962 as a coronary vasodilator. Vera Pammy, also called verapamil, is an calcium channel blocker. In recent years, it has been used for the treatment of hypertension, angina pectoris, arrhythmia, cerebrovascular disease, finger vascular spasm, abdominal pain, esophageal atony, migraine, pulmonary hypertension and premature delivery. Chinese name Veerappa, another name for verapamil, verapamil, Mai an, Van La Pammy, verapamil, stop English name, VerapamilM, FC27H38N2O4M, W454.6CAS52-53-9 directory, 1 drug name 2 characters 3 storage 4 function and use 5 pharmacological pharmacokinetics 6 indications 7 usage and dosage 8 adverse reactions 9 contraindications 10 drug interactions 11 note 1 drug name editor Molecular formula English alias: Cordilox, Iproveratril, Veraloc, Verapamilum, IproveratrilISOPTIN 2 character editing tablets, injections. Commonly used in its hydrochloride, white powder; odorless. Soluble in methanol, ethanol, or chloroform and dissolved in water. Melting point 140 DEG C, 145 DEG C. 3 store, edit, shade and seal. 4 role and use as a calcium channel blocker (calcium antagonist). Inhibition of calcium influx reduces the rate of automatic diastolic depolarization of the heart, verapamil The release of the sinoatrial node slows and slows the conduction. It can slow forward conduction, and thus can eliminate atrioventricular nodal reentry. Peripheral blood vessels dilate and cause blood pressure to drop, but they are weak, which can cause heart rate to slow down, but can also reduce the reflex heart rate due to the decrease of blood pressure. It can relax the coronary artery, increase the coronary flow, improve the oxygen supply of the myocardium, and, in addition, inhibit the aggregation of platelet. 5 pharmacology, pharmacokinetics, editing, pharmacodynamics Is a class IV antiarrhythmic drugs, a calcium influx inhibitor (slow channel blocker), in the heart, r-
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