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methods for food safety IACM（食品安全发展的方法）.pdf

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methods for food safety IACM（食品安全发展的方法）

ISO 16140 validated alternative methods for food safety 1 1 2 2 2 D. Sohier , M. Rannou , C. Sidi , C. Cordevant , F. Martinez 1 ADRIA Développement 2 BIO-RAD SUMMARY • Alternative methods Alternative methods • ISO 16140 standard • Applications : validated methods … ¸Bio-Rad alternative methods ! Qualitative and quantitative Alternative methods • European regulation for food safety (Regulation (EC) No 852/2004) specified Alternative methods are validated against the reference method; the results are certified by a third party in accordance with the protocol set out in EN/ISO standard 16140 or other internationally accepted similar protocols Alternative methods • The tests are validated by an expert lab according to ¸ISO 16140 protocol in Europe ¸AOAC-RI and AOAC-OMA in the US • The results are presented and certified by a third party : ¸AFNOR in France ¸AOAC in the US ¸NORDVAL in Northern Europe ¸Microval will be the European committee? SUMMARY • Alternative methods ISO 16140 Standard • ISO 16140 standard • Applications : validated methods … ¸Bio-Rad alternative methods Qualitative and quantitative ISO 16140 : qualitative method ¸Preliminary study made by the expert lab • Specificity : Inclusivity and Exclusivity • Relative detection limit • Relative, accuracy, specificity and sensibility ¸Collaborative study with 10 labs at least • Reliability ¸… Practicability! ISO 16140 : quantative method ¸Preliminary study made by the expert lab • Linearity • Accuracy • Relative detection limit (in