multiple loci within the major histocompatibility complex confer risk of psoriasis多个位点在牛皮癣的主要组织相容性复合体带来风险.pdfVIP

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multiple loci within the major histocompatibility complex confer risk of psoriasis多个位点在牛皮癣的主要组织相容性复合体带来风险.pdf

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multiple loci within the major histocompatibility complex confer risk of psoriasis多个位点在牛皮癣的主要组织相容性复合体带来风险

Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis 1. 3,4. 1 5 6 Bing-Jian Feng , Liang-Dan Sun , Razieh Soltani-Arabshahi , Anne M. Bowcock , Rajan P. Nair , 6 6 7 7¤a 8 Philip Stuart , James T. Elder , Steven J. Schrodi , Ann B. Begovich , Gonc¸alo R. Abecasis , Xue-Jun 2,3,4 1 1 1 Zhang , Kristina P. Callis-Duffin , Gerald G. Krueger , David E. Goldgar * 1 Department of Dermatology, University of Utah School of Medicine, Salt Lake City, United States of America, 2 Institute of Dermatology, Anhui Medical University, Hefei, China, 3 Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China, 4 Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, China, 5 Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America, 6 Department of Dermatology, University of Michigan, Ann Arbor, Michigan, United States of America, 7 Celera, Alameda, California, United States of America, 8 Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America Abstract Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249