有哪些信誉好的足球投注网站hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats硫化氢变弱碳tetrachloride-induced肝毒性,肝硬化和门脉高压大鼠.pdfVIP
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hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats硫化氢变弱碳tetrachloride-induced肝毒性,肝硬化和门脉高压大鼠
Hydrogen Sulfide Attenuates Carbon Tetrachloride- Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats 1 1 3 1 2 2 1 Gang Tan , Shangha Pan , Jie Li , Xuesong Dong , Kai Kang , Mingyan Zhao , Xian Jiang , Jagat R. 4 1 1 1,5 Kanwar , Haiquan Qiao , Hongchi Jiang *, Xueying Sun * 1 Department of General Surgery, The Hepatosplenic Surgery Center, The First Affiliated Hospital of Harbin Medical University, Harbin, China, 2 Department of ICU, The First Affiliated Hospital of Harbin Medical University, Harbin, China, 3 Department of Hepatobiliary Surgery, Affiliated Qianfoshan Hospital of Shandong University, Jinan, China, 4 Laboratory of Immunology and Molecular Biomedical Research, Centre for Biotechnology and Interdisciplinary Biosciences, Institute for Technology and Research Innovation, Deakin University, Geelong, Victoria, Australia, 5 Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand Abstract Background: Hydrogen sulfide (H S) displays vasodilative, anti-oxidative, anti-inflammatory and cytoprotective activities. 2 Impaired production of H2S contributes to the increased intrahepatic resistance in cirrhotic livers. The study aimed to investigate the roles of H S in carbon tetrachloride (CCl )-induced hepatotoxicity, cirrhosis and portal hypertension. 2 4 Methods and Findings: Sodium hydrosulfide (NaHS), a donor of H S, and DL-propargylglycine (PAG), an irreversible
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