有哪些信誉好的足球投注网站high prevalence of hepatitis c virus genotype 1b infection in a small town of argentina. phylogenetic and bayesian coalescent analysis丙型肝炎病毒基因型1 b感染高发的一个小镇上的阿根廷。.pdfVIP
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high prevalence of hepatitis c virus genotype 1b infection in a small town of argentina. phylogenetic and bayesian coalescent analysis丙型肝炎病毒基因型1 b感染高发的一个小镇上的阿根廷。
High Prevalence of Hepatitis C Virus Genotype 1b Infection in a Small Town of Argentina. Phylogenetic and Bayesian Coalescent Analysis 1 1 2 3 3 Marcelo D. Golemba , Federico A. Di Lello , Fernando Bessone , Fabian Fay , Silvina Benetti , Leandro R. 4 1 Jones , Rodolfo H. Campos * ´ ´ ´ 1 Catedra de Virologıa, Facultad de Farmacia y Bioquımica, Universidad de Buenos Aires, Buenos Aires, Argentina, 2 Hospital Provincial del Centenario, Servicio de ´ ´ Gastroenterologıa y Hepatologıa, Universidad Nacional de Rosario, Rosario, Argentina, 3 Laboratorio Cibic-Rosario, Rosario, Argentina, 4 Division of Molecular Biology, ´ ´ ´ Estacion de Fotobiologıa Playa Union, CC 15, (9103) Rawson, Chubut, Argentina Abstract Previous studies in Argentina have documented a general prevalence of Hepatitis C Virus (HCV) infection close to 2%. In addition, a high prevalence of HCV has been recently reported in different Argentinean small rural communities. In this work, we performed a study aimed at analyzing the origins and diversification patterns of an HCV outbreak in Wheelwright, a small rural town located in Santa Fe province (Argentina). A total of 89 out of 1814 blood samples collected from people living in Wheelwright, were positive for HCV infection. The highest prevalence (4.9%) was observed in people older than 50 years, with the highest level for the group aged between 70–79 years (22%). The RFLP analyses showed that 91% of the positive samples belonged to the HCV-1b genotype. The E1/E2
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