henipavirus rna in african bats中存在亨德拉尼帕病毒rna便是非洲的蝙蝠.pdfVIP

Henipavirus RNA in African Bats 1,2. 2. 3 3 4 Jan Felix Drexler , Victor Max Corman , Florian Gloza-Rausch , Antje Seebens , Augustina Annan , 3 1,4 ¨ 2 5,6 7 Anne Ipsen , Thomas Kruppa , Marcel A. Muller , Elisabeth K. V. Kalko , Yaw Adu-Sarkodie , Samuel Oppong7, Christian Drosten 1,2* 1 Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, 2 Institute of Virology, University of Bonn Medical Centre, Bonn, Germany, 3 Noctalis, Centre for Bat Protection and Information, Bad Segeberg, Germany, 4 Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana, 5 Institute of Experimental Ecology, University of Ulm, Ulm, Germany, 6 Smithsonian Tropical Research Institute, Balboa, Panama, 7 Kwame Nkrumah University of Science and Technology, Kumasi, Ghana Abstract Background: Henipaviruses (Hendra and Nipah virus) are highly pathogenic members of the family Paramyxoviridae. Fruit- eating bats of the Pteropus genus have been suggested as their natural reservoir. Human Henipavirus infections have been reported in a region extending from Australia via Malaysia into Bangladesh, compatible with the geographic range of Pteropus. These bats do not occur in continental Africa, but a whole range of other fruit bats is encountered. One of the most abundant is Eidolon helvum, the African Straw-coloured fruit bat. Methodology/Principal Findings: Feces from E. helvum roosting in an urban setting in Kumasi/Ghana were tested for Henipavirus RNA. Sequences of three novel viruses in phy