参附注射液-氨茶碱-纳洛酮及贝美格对老年患者全身麻醉苏醒质量对比探究.docVIP

参附注射液\氨茶碱\纳洛酮及贝美格对老年患者全身麻醉苏醒质量对比探究摘 要：目的：探讨参附注射液、氨茶碱、纳洛酮和贝美格对老年患者全身麻醉苏醒质量。方法：全身麻醉下行择期腹部手术老年患者100例，按随机数字表法分为参附注射液组、氨茶碱组、纳洛酮组、贝格美组和对照组各20例。结果：参附注射液组、氨茶碱组、纳洛酮组、贝格美组的T1、T2和T2比对照组短（P＜0.05）；苏醒时间：纳洛酮组＜贝美格组＜氨茶碱组＜参附注射液组＜对照组。纳洛酮组和贝格美组的HR和MAP在拔管即刻和拔管后5min均高于对照组（P＜0.05），参附注射液组与对照组无差异（P＞0.05），氨茶碱组HR高于对照组（P＜0.05），MAP无差异（P＞0.05）；对照组、氨茶碱组、纳洛酮组、贝美格组不良反应分别为10.0%（2/20）、30.0%（6/20）、35.0%（7/20）、25.0%（5/20），参附注射液组无不良反应。结论：参附注射液能明显加快全身麻醉苏醒，血液动力学平稳，心率和血压波动小，无明显不良反应，是一种安全、有效的老年患者全身麻醉促醒药物，值得临床推广应用。 关键词：参附注射液；氨茶碱；纳洛酮；贝美格；苏醒质量；老年；全身麻醉 中图分类号：R285.5文献标识码：B 文章编号：1673-7717（2011）04-0932-03 The Comparison Study of Shenfu Injection,Aminophylline,Naloxone and Bemegride on the Quality of Recovery From General Anaesthesia in Old Patients TANG Ru【sup】1【/sup】,DONG Mei-zhen【sup】2【/sup】,GUO Ting【sup】1【/sup】, XIA Xun【sup】1【/sup】 （1.Department of Anesthesiology,The First People’s Hospital of Tonglu County,Tonglu 311500, China 2.Department of Anesthesiology, Tonglu Chinese Medicine Hospital, Tonglu 311500, China） Abstract:Objective: To investigate the shenfu injection, aminophylline, naloxone and bemegride on the quality of recovery from general anaesthesia in old patients. Method: One hundred old patients undergoing elective abdominal operation with general anaesthesia were divided into shenfu injection group, aminophylline group, naloxone group, bemegride group and control group with 20 patients in each group according to the random digits table method. Results: The T1, T2 and T2 of shenfu injection group, aminophylline group, naloxone group, and bemegride group were shorter than control group （P＜0.05）Awakening time: naloxone group＜bemegride group＜aminophylline group＜shenfu injection group＜control group. The HR and MAP in naloxone group and bemegride group were higher than control group at the time of extubation immediately and 5 min after extubation （P＜0.05）, and there is no difference in shenfu injection group and control group （P＞0.05）HR in aminophylline group was higher than contr