儿童过敏性紫癜87例临床特点研究.docVIP

儿童过敏性紫癜87例临床特点研究[摘要] 目的 通过回顾分析我院87例儿童过敏性紫癜的临床资料，总结该病的临床特点。方法 将87例儿童过敏性紫癜的临床资料，包括病史、实验室检查、治疗方法等作总结归类分析。结果 87例儿童过敏性紫癜中，除皮肤紫癜外，关节肿痛者占49.4%；消化道症状者达47.1%，其中1例腹痛患者为肠套叠；肾脏受损者达24.1%。结论 儿童过敏性紫癜在发生典型的皮肤紫癜前可有腹痛等非特异表现，易导致误诊；合并多脏器损害的患者应当及时采取相应治疗措施，争取早期治愈。 [关键词] 过敏性紫癜； 临床表现；儿童 [中图分类号] R725[文献标识码] A[文章编号] 1005-0515（2011）-05-005-01 Clinical Features of 87 Children with Henoch-Schonlein purpura, a Report of 87 Cases Shi Yan (Department of pediatrics, Chinese medicine hospital of xishui county, Hubei Province, China 438200) [Abstract] Objective Retrospectively analyzed the clinical information of 87 patients with Henochhonlein purpura, the clinical features of the disease were reviewed. Methods clinical data, including medical history, laboratory tests and treatment, of 87 cases of children with Henoch-Sehonlein purpura were classified and analyzed. Results 87 cases of children with Henoch-Sehonlein purpura, in addition to skin purpura, joint swelling and pain accounted for 49.4%; gastrointestinal symptoms were 47.1%, including 1 case of abdominal pain as intussusception; kidney damage were 24.1%. Conclusions For Henoch-Sehonlein purpura in children, the event before the typical skin purpura may have abdominal pain and other non-specific manifestation, easily lead to misdiagnosis; patients with multiple organ damage should be treated promptly and take appropriate measures for early cure. [Keywords] Henoch-Sehonlein purpura; clinical situation; children 过敏性紫癜是一种常见于儿童的系统性毛细血管变态反应性疾病。临床特点为非血小板减少性紫癜，关节炎，腹痛，肾炎等。该病的病因至今未明，但通常转归良好。值得注意的是，并发胃肠症状和侵犯肾脏的过敏性紫癜可以产生严重后果，应当引起临床医生的警惕。该病的临床转归通常与是否存在肾脏累及有关。而首发症状为胃肠道症状，关节症状等非特异表现的患者通常导致临床误诊误治。本文回顾我院2000年-2010年间所有住院治疗的过敏性紫癜患者的临床资料，着重总结伴有胃肠道症状，关节症状，累及肾脏等皮肤外非特异损害的临床特点。 1 对象和方法 1.1 病例对象 所有入选病例都是曾经在我院住院，并经过本院或外院确诊的过敏性紫癜患者，均符合《诸福堂实用儿科学》提出的诊断标准[1]。在所有95例患者中，2例因病情严重转诊，其余6例失访，纳入统计87例。 1.2 方法 分别统计患者的症状，体征，合并症以及治疗转归等。 2 结果 2.1 病例一般情况 在87例患者中，男患儿51例（58.6%），女患儿36例（41.4%），男女比例为1.41。平均发病年龄为8.12±3.22岁。皮肤，关节，胃肠和肾脏累及者分别占100%，49.4%，