2型糖尿病胰岛素抵抗的炎症机制与中医药辨治（Inflammatory mechanisms and TCM syndrome differentiation treatment on insulin resistance in type 2 diabetes）.docVIP

2型糖尿病胰岛素抵抗的炎症机制与中医药辨治（Inflammatory mechanisms and TCM syndrome differentiation treatment on insulin resistance in type 2 diabetes） Inflammatory mechanisms and TCM syndrome differentiation treatment on insulin resistance in type 2 diabetes Update: 10-11 [Abstract] the occurrence and development of type 2 diabetes and inflammation are closely related, inflammatory factors can cause insulin resistance and insulin secretion dysfunction, inflammatory factors including TNF alpha, IL 6, CRP, adiponectin, MCP 1 etc.. Chinese medicine treatment of diabetes has rich clinical experience, that the etiology and pathogenesis and spleen deficiency on the insulin resistance, the use of Chinese medicine therapy adjustmentdiabetic inflammation, improve insulin resistance. [Key words] type 2 diabetes / insulin / TCM therapy; pharmacodynamics; inflammation Type 2 diabetes mellitus (Type 2 diabetes mellitus, T2DM) in the etiology and pathogenesis has not been fully elucidated. Recent studies showed that T2DM and its complications occurred with the development of T2DM is closely related to inflammation, innate immunity and low-grade chronic inflammatory diseases. T2DM in susceptible individuals, with aging and nutrition and the role of environmental factors, the innate immune system was activated, 6 macrophages and other inflammatory factors, fat cells and sentinel cells secrete TNF alpha, IL, and lead to insulin resistance (insulin resistance, IR), insulin secretion dysfunction. Chinese medicine for the treatment of diabetes mellitus with rich clinical experience, and T2DM for chronic inflammation, prevention and treatment of diabetes of TCM research, will help to improve the clinical effect and to clarify its mechanism of action. The existing studies have shown that IR and insulin secretion dysfunction may not be independent of each other, if it is determined that autocrine insulin functions, then islet beta cell IR two seems to be the bridge to connect them, there may be effects of in