短期摄食卵黄磷脂与鱼油对高脂小鼠脂质代谢的影响.PDFVIP

现代食品科技 Modern Food Science and Technology 2017, Vol.33, No.7 短期摄食卵黄磷脂与鱼油对高脂小鼠脂质代谢 的影响 史豪豪，车红霞，高翔，崔洁，王玉明，薛长湖 （中国海洋大学食品科学与工程学院，山东青岛 266003） 摘要：比较研究短期摄食磷脂型（Docosahexaenoic acid, DHA)、甘油三酯型DHA 以及甘油三酯型DHA 与卵黄磷脂复合物对高 脂小鼠脂质代谢的影响。C57BL/6J 小鼠按体重分为5 组，低脂对照组、高脂模型组、磷脂型 DHA 组、甘油三酯型 DHA 组、甘油三 酯型DHA 与蛋黄磷脂的复配组，各受试物组均采用高脂饲料，喂食一周后，分别测定血清、肝脏和脑内的脂质水平以及肝脏和脑内 的脂肪酸组成。短期膳食补充 DHA 后均可不同程度改善小鼠的脂质代谢。磷脂型 DHA 以及甘油三酯型 DHA 与蛋黄磷脂的复配同 等程度显著降低了高脂摄食小鼠的血清 TG 浓度；而在降低 TC 方面，磷脂型 DHA 效果优于复配型；甘油三酯型 DHA 与卵黄磷脂 的复配组肝脏TG 水平显著低于高脂组，但与磷脂型DHA 组无显著差异；磷脂型 DHA 与复配型均显著提高肝脏和脑内DHA 含量。 磷脂型 DHA 能够更有效改善高脂饮食小鼠血清和肝脏脂质代谢，且磷脂型DHA 在增加脑内 DHA 方面效果最佳。 关键词：脂质代谢；二十二碳六烯酸；甘油三酯；磷脂；脂肪酸组成 文章篇号：1673-9078(2017)7-9-16 DOI: 10.13982/j.mfst.1673-9078.2017.7.002 Effects of Short-term Consumption of Fish Oil-egg-phospholipid on Lipid Metabolism in Mice Fed a High-fat Diet SHI Hao-hao, CHE Hong-xia, GAO Xiang, CUI Jie, WANG Yu-ming, XUE Chang-hu (College of Food Science and Technology, Ocean University of China, Qingdao 266003, China) Abstract: The effects of short-term consumption of docosahexaenoic acid (DHA)-enriched phospholipids, DHA-enriched triglycerides, and the combination of DHA-enriched triglycerides and egg-phospholipids on lipid metabolism in mice fed a high-fat diet were compared. C57BL/6J mice were divided into five groups: low-fat group, high-fat group, DHA-enriched phospholipid group, DHA-enriched triglyceride group, and DHA-enriched triglyceride-egg-phospholipids combination group. Mice were fed the high-fat diet for a week; thereafter, lipid levels in the serum, liver, and brain wer