DNA芯片技术与基因表达研究.PDF

4 2 生命科学研究 Vol. 4 No. 2 2 0 0 0 6 Life Science Research Jun. 2000 : 1007-7847(2000) 02-0106-06 DNA 1, 2 1 2 祝　骥 , 马文丽, 姚汝华 ( 1. , 10 1 ; 2. , 10460) : 随着基因组计划的顺利实施, 大量的生物信 被解析, 基因表达及基因功能的研究 将成为生命科学研究的热点. DNA 芯片技术是近年来出现的分子生物学与微电子技术相结 合的必威体育精装版DNA 分析检测技术. 该技术将在生命科学与信 科学之间架起 一道桥梁, 因而成 为后基因组时代基因功能分析的最重要的技术之一. 目前DNA 芯片技术已在基因表达等研 究中得到广泛的应用. : DNA 芯片; 基因表达; 生物信 学 : Q786: A DNA Chip Technology and the Studies of Gene Expression 1, 2 1 2 , - , - ZHU Ji MA Wen li YAO Ru hua ( 1. Instit ut e of Molecular Biology , First Military M edical Universit y, Guangzhou 10 1 , Guangdong, China; 2. Bio-science Engineering Research Center, South China University of Technology, Guangzhou 10640 , , ) Guangdong China Abstract With the implementing of Human Genomic Project and analyzing of a large: amount of bioinformation, the studies of gene expression and gene function will become the hot spot of life sciences. DNA chip technology is the latest DNA analysis and examining technology w hich combined molecular biology w ith microelectronics This technology w ill. build up a bridge betw een bio-science and information science, and become one of the most important technologies for gene function analysis in the postgenomics for its treatments of , , . parallel large quantity miniature and automation DNA chip technology has been w idely applied in the gene expression now . Key words: DNA chips; gene expression; bioinformatics : 2000-03-07 : ( : ( 1967-) , , , , , T el: 020-8 14836, E -mail: Zh