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英文课件-引言
Biochemistry Introduction What is Biochemistry? Describe structure, organization, function of cells in molecular terms. Structural Chemistry Metabolism Molecular Genetics Biochemistry as a Discipline Biochemistry as a Chemical Science Amino acids Sugars Lipids Nucleotides Vitamins Hormones Chemical Elements of Living Matter Monomers/Polymers Sugar/Polysaccharide Nucleotide/Nucleic Acids Amino acid/Polypeptides Biochemistry as a Biological Science Distinguishing Characteristics of Living Matter Constant renewal of a highly ordered structure accompanied by an increase in complexity of that structure Overcoming entropy requires energy Life is self-replicating Range of sizes of objects studied by biochemists and biologists Uses of Biochemistry Agriculture: Herbicides and pesticides Medicine : Monocloning antibodies Nutrition : Vitamines Clinical Chemistry: transaminases and bilirubin/Liver disease Pharmacology: penicillin (inhibiting an enzyme that synthesizes an essential polysaccharide of the bacterial cell wall) Toxicology: designer drugs If the target site for action of a drug is a protein enzyme or receptor, determining the detailed molecular structure of that target allows us to design inhibitors that bind to it with great selectivity. End * AZT was the first drug approved in the United States for the treatment of HIV infections. This nucleoside is anabolized to the corresponding 5 triphosphate, which acts as an inhibitor of viral reverse transcriptase in making DNA from the viral RNA *
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