第9章_Freehand_Elastography徒手弹性成像.pdfVIP

Technical Advance Diagnosing Cysts With Correlation Coefficient Images From 2-Dimensional Freehand Elastography Rebecca C. Booi, PhD, Paul L. Carson, PhD, Matthew O’Donnell, PhD, Michael S. Richards, PhD, Jonathan M. Rubin, MD, PhD Objective. We compared the diagnostic potential of using correlation coefficient images versus elas- tograms from 2-dimensional (2D) freehand elastography to characterize breast cysts. Methods. In this preliminary study, which was approved by the Institutional Review Board and compliant with the Health Insurance Portability and Accountability Act, we imaged 4 consecutive human subjects (4 cysts, 1 biopsy-verified benign breast parenchyma) with freehand 2D elastography. Data were processed offline with conventional 2D phase-sensitive speckle-tracking algorithms. The correlation coefficient in the cyst and surrounding tissue was calculated, and appearances of the cysts in the correlation coeffi- cient images and elastograms were compared. Results. The correlation coefficient in the cysts was con- siderably lower (14%–37%) than in the surrounding tissue because of the lack of sufficient speckle in the cysts, as well as the prominence of random noise, reverberations, and clutter, which decorrelated quickly. Thus, the cysts were visible in all correlation coefficient images. In contrast, the elastograms associated with these cysts each had different elastographic patterns. The solid mass in this study did