蛋清高F值寡肽对受试小鼠脏器影响的研究.PDF

※营养卫生 食品科学 2008, Vol. 29, No. 11 601 张文博，刘静波，王 莹， 钟天一，王世巍， 林松毅 * (吉林大学军需科技学院营养与功能食品研究室，吉林 长春 130062) 目的：给小鼠灌胃不同浓度的蛋清高F 值寡肽后，测定小鼠的脏器重量、脏器系数，检验对胸腺、脾、 心、肝、肾、肺的影响。方法：选用未成年小鼠 8 0 只，分别测定 6 个脏器重量，计算脏器系数，探究比较 相同脏器不同浓度组之间的差异，分析差异的原因以及对机体的影响。结果：与空白组对比，5% 蛋清多肽液实 验组和 5% 蛋清高F 寡肽液实验组的受试小鼠脾脏脏器系数差异显著(p0.01)，20% 蛋清高F 寡肽液实验组的受试小 鼠胸腺脏器系数差异显著(p0.01) 。结论：与蒸馏水对比，5% 蛋清高F 寡肽液对小鼠的免疫器官有积极作用，可 以提高小鼠的免疫力；10% 蛋清高F 寡肽液对小鼠肝功能有积极的促进作用；15% 蛋清高F 寡肽对小鼠的免疫能力 有积极的影响。 蛋清高 F 值寡肽；脏器系数；脏器重量差 Effects of High F Value Oligopeptide from Egg White on Mouse Organs ZHANG Wen-bo ， LIU Jing-bo ，WANG Ying ，ZHONG Tian-yi ，WANG Shi-wei ，LIN Song-yi* (Laboratory of Nutrition and Function Food, College of Quartermaster Technology, Jilin University, Changchun 130062, China) Abstract：Objective: By the way of intragastric administration to mice with different concentrations of high F value oligopeptide from egg white, the weights and coefficients of heart, liver, kidney, spleen, lung and thymus of mice were measured, respectively. Methods: Eighty immature mice were selected. Their six organ weights were measured respectively, and the organ coefficients were calculated. The difference among identical organ groups with different concentrations of the high F value oligopeptide and the differential reason and influence on organism were analyzed. Results: The differences of spleen coefficients between blank group and 5% high F value oligopeptide and 5% polypeptide experimental group are great (p0.01). The differences of thymus coefficients between blank group and 20% polypeptide experimental group are greats (p0.01). Conclusions: 5% high F value oligopeptide has positive effect on immune organs and immunity of mice;