ARFI声辐射力脉冲成像技术NAFLD.pdfVIP

518 J Clini Hepatol, May 2011, Vol.27, No.5 论著/脂肪性肝病 非酒精性脂肪性肝病患者肝脏声辐射力 脉冲成像的临床观察 1 2 1 1 1 1 1 1 1 张大鹍 ，赵媛媛 ，李志艳 ，陈 敏 ，刘 阳 ，谢 跃 ，董晓宇 ，周艳贤 ，苏 颖 (1 解放军第三○二医院超声科，北京 100039；2 青岛市市立医院超声科，山东 青岛 266071) 摘要：目的 探讨声辐射力脉冲成像(ARFI)技术评价非酒精性脂肪性肝病(NAFLD)患者肝脏弹性的临床价值。方法 分别对 76例NAFLD患者和30例健康对照者应用声辐射力脉冲成像技术进行肝脏弹性的检测 ，比较并分析各组间肝脏弹性定量参数的差 异。结果 NAFLD组与对照组间ARFI测值差异具有统计学意义(P ＜0.0 1) ，NAFLD不同程度组间ARFI测值差异具有统计学意义 (P ＜0.0 1) ，重度与轻 、中度组比较 ，差异具有统计学意义(P ＜0.0 1) 。随NAFLD患者脂肪肝程度的加重 ，肝脏的ARFI测值也逐 r P ＜ 结论 渐增高 ，两者存在正相关( =0.453 ， 0.01)。 声辐射力脉冲成像技术不仅无创 ，更可较准确的对NAFLD患者肝脏弹性进 行定量评价。 关键词：脂肪肝；弹性成像技术 中图分类号： 文献标识码： 文章编号： （ ） R575.5 A 1001-5256 2011 05-0518-03 The initial study of quantitative evaluation of the degree of non-alcoholic fatty liver disease by acoustic radiation force impulse imaging ZHANG Da-kun, ZHAO Yuan-yuan, LI Zhi-yan, et al. (Department of Ultrasound, the 302 Hospital of PLA, Beijing 100039, China) Abstract: Objective To investigate the clinical value of the acoustic radiation force impulse (ARFI) technique in the quantitative evaluation of non-alcoholic fatty liver disease. Methods 76 patients with non-alcoholic fatty liver disease and 30 normal healthy controls were examined using acoustic radiation force Impulse technique. Results The parameter of ARFI in non-alcoholic fatty liver disease group was significantly lower than that in the control group(P0.01). In non-alcoholic fatty liver disease patients, there were significant differences in the parameter of ARFI among the mild, moderate and severe fatty liver groups(P0.01). The difference in ARFI between the s