从大猩猩的基因组序列深入了解人类进化.docxVIP

-------------------------------- Insights into hominid evolution from the gorilla genome sequence 从大猩猩的基因组序列深入了解人类进化 ---------------------------------------------------------- Aylwyn Scally1, Julien Y. Dutheil2{, LaDeana W. Hillier3, Gregory E. Jordan4, Ian Goodhead1{, Javier Herrero4, Asger Hobolth2,Tuuli Lappalainen5, Thomas Mailund2, Tomas Marques-Bonet3,6,7, Shane McCarthy1, Stephen H. Montgomery8, Petra C. Schwalie4, Y. Amy Tang1, Michelle C. Ward9,10, Yali Xue1, Bryndis Yngvadottir1{, Can Alkan3,11, Lars N. Andersen2, Qasim Ayub1, Edward V. Ball12, Kathryn Beal4, Brenda J. Bradley8,13, Yuan Chen1, Chris M. Clee1, Stephen Fitzgerald4, Tina A. Graves14, Yong Gu1, Paul Heath1, Andreas Heger15, Emre Karakoc3, Anja Kolb-Kokocinski1, Gavin K. Laird1, Gerton Lunter16, Stephen Meader15, Matthew Mort12, James C. Mullikin17, Kasper Munch2, Timothy D. O’Connor8, Andrew D. Phillips12, Javier Prado-Martinez6, Anthony S. Rogers1{, Saba Sajjadian3, Dominic Schmidt9,10, Katy Shaw12, Jared T. Simpson1, Peter D. Stenson12, Daniel J. Turner1{, Linda Vigilant18, Albert J. Vilella4, Weldon Whitener1, Baoli Zhu19{, David N. Cooper12, Pieter de Jong19, Emmanouil T. Dermitzakis5, Evan E. Eichler3,11, Paul Flicek4, Nick Goldman4, Nicholas I. Mundy8, Zemin Ning1, Duncan T. Odom1,9,10, Chris P. Ponting15, Michael A. Quail1, Oliver A. Ryder20, Stephen M. Searle1, Wesley C. Warren14, Richard K.Wilson14, Mikkel H. Schierup2, Jane Rogers1{, Chris Tyler-Smith1 Richard Durbin1 人名------------------------------------------------------------------------------ Gorillas are humans’ closest living relatives after chimpanzees, and are of comparable importance for the study of humanorigins and evolution. Here we present the assembly and analysis of a genome sequence for the western lowland gorilla,and compare the whole genomes of all extant great ape genera. We propose a synthesis of genetic and fossil evidence consistent with placing the human–chimpanzee and human–chimpanzee–gorilla speciation