有机化学chap02stereochemistry2.pptVIP

* * * * 1951年J.M.Bijvoet通过X射线分析法，测得了右旋酒石酸铷钠盐的构型，这种实际测定得构型称为绝对构型。因此推出人为规定的甘油醛的构型与实际的构型完全符合。 * * * * * * * * * * * * * * * * 巴斯德(Pasture)发现结晶洒石酸，左旋体半面结晶向左，右旋体半面结晶向右。在放大镜下，他用镊子分开两种酒石酸。 * ?Louis Pasteur?was the first to conduct chiral resolution when he discovered the concept of?optical activity?by the manual separation of left-handed and right-handed?tartaric acid?crystals in 1849. In 1882 he went on to demonstrate that by?seeding?a?supersaturated?solution of?sodium ammonium tartrate?with a d-crystal on one side of the reactor and a l-crystal on the opposite side, crystals of opposite handedness will form on the opposite sides of the reactor. * * * * * * * * * * * * * * * * * * 方解石（英语：calcite）是碳酸钙（CaCO3）的稳定形态，呈现棱面体或偏三角面体，聚形呈钉头或犬牙状。其中，棱面晶体有双折射性。 * * * 低压钠灯工作时,在可见光区发射出两条极强的黄色谱线(又称D线),它们是由中心波长?1 =589.0nm和?2=589.6nm的双线组成,波长差为0.6nm.每一条谱线有一定的宽度,由于双线波长差??与中心波长相比很小,可以看做准单色光.通常取它们的中心近似值589.3nm作为钠黄光的标准参考波长 * * * * 紫彬醇30mg/5ml ，零售价格：560元/支 * * * * * * * * * * * Section 8. Resolution of Enantiomers 外消旋体拆分（resolution）：将外消旋体分离成两个对映异构体。也称为手性拆分（chiral resolution）或光学拆分（optical resolution） * Louis Pasteur (路易斯?巴斯德，1822-1895) * Louis Pasteur (1822-1895) PhD in crystallography Professor of Physics (Dijon), of Chemistry (University of Strasbourg), of Organic Chemistry (Sorbonne, Paris) Member of the Academy of Science (mineralogy section). Professor as a Medical Doctor at the University of Bonn. His research Relationships between crystalline forms, chemical composition and the rotatory polarisation. discovery of the transformation of tartaric acid into racemic acid, discovery of the optically inactive tartaric acid. researches on lactic and alcoholic fermentation(发酵)and on beer Studies on wine diseases Studies on silkworm diseases, work on pasteurisation(巴氏灭菌法) Studies on anthrax(炭疽), septicaemia(败血病), chicken cholera(鸡霍乱). Introduction of the principle of attenuated-virus vaccines(减毒病毒疫苗) Vaccination against swine erysipelas(豚丹毒)using an attenuated-virus vaccine. First ant