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Downloaded from / on June 8, 2017 - Published by Basic science ORIGINAL RESEARCH Human placenta as an ex vivo vascular model for neurointerventional research John Ching Kwong Kwok,1,2 Wei Huang,3 Wing-Cheong Leung,4 Siu-Ki Chan,5 Kwong-Yau Chan,1 Kar-Ming Leung,1 Alberto Chi Ho Chu,1 Alexander Kar Ngai Lam3 1Department of Neurosurgery, ABSTRACT METHODS Kwong Wah Hospital, Background Human placenta is a convenient resource Written consent for donation of placenta for Kowloon, Hong Kong for biomedical research, and has not yet been used for research was obtained from the mother before the 2Division of Biomedical Engineering, Hong Kong neurointerventional surgery research. baby was delivered. Eighteen placentas were University of Science and Objective Our objective was to explore the feasibility obtained during the period 2011–2013 for various Technology, Kowloon, of using human placenta to test various endovascular vascular interventions. Fresh placentas soon after Hong Kong interventions and for training. delivery were used. After cleansing with normal 3Department of Mechanical Engineering, Hong Kong Design 18 placentas soon after delivery were prepared sterile saline solution to remove any blood adhered University of Science and for six pilot studies. (1) Study on anatomical similarity to to the placenta surface, the amnion sac was peeled Technology, Kowloon, Hong human cerebral vessel. (2) Simula