结直肠癌文献更新7月刊-EX.pdfVIP

COLORECTAL CANCER PUBLICATION ALERT JULY 2014 结直肠癌文献更新 ■ 本回复仅为学术交流之目的供中华人民共和国境内医学专业人士参考。 医疗卫生专业人士做出的任何与治疗有关的决定应参考国家食品药品监督管理总局批准的药品说明书 ； 详见 未经授权 ，该资料不得翻印或散发 目录 COLORECTAL CANCER JULY 2014 Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review. 结直肠癌中 KRAS 密码子 61 和密码子 146 突变的临床病理、分子学和预后关联的分析：队列研究与文献综述 4 Colorectal signet-ring cell carcinoma: Benefit from adjuvant chemotherapy but a poor prognostic factor. 结直肠印戒细胞癌：从辅助化疗中受益，但是预后较差因子 6 The COLON study: Colorectal cancer: Longitudinal, Observational study on Nutritional and lifestyle factors that may influence colorectal tumour recurrence, survival and quality of life. COLON 研究：结直肠癌：可能影响结直肠肿瘤复发、生存和生活质量的营养和生活方式因素的纵向观察性研 究 7 Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. 东亚人群中鉴别 6 个与结直肠癌风险相关的基因位点的大规模遗传研究 9 Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial. 奥沙利铂、氟尿嘧啶和亚叶酸联合或不联合西妥昔单抗在手术切除的Ⅲ期结肠癌患者（PETACC-8 ）中的疗效： 一项开放性、随机 3 期临床试验 10 Management of colorectal cancer presenting with synchronous liver metastases. 表现出同步性肝转移的结直肠癌的管理 12 Patient and Tumor Characteristics and BRAF and KRAS Mutations in Colon Cancer, NCCTG/Alliance N0147. 结肠癌患者和肿瘤特征以及 BRAF 和 KRAS 突变，NCCTG/联盟 N0147 研究 13 Should colorectal cancer screening be considered in elderly persons without previous screening?: a cost-effectiveness analysis. 之前未进行筛查的老年人中是否应该考虑进行结直肠癌筛查？：一项成本效应分析 14 Molecular testing for lymph node metastases as a determinant of colon cancer recurrence: results from a retrospective multicenter study. 为淋巴结转移进行分子学检测作为结肠癌复发的决定因素：一项回顾性多中心研究的结果 16 Twelve-year experience of radioembolization for colorectal hepatic metastase