我院2011_2013年质子泵抑制剂应用分析.pdfVIP

我院2011－2013年质子泵抑制剂应用分析 ＊ # 朱爱国 ，王 建，张桂芬（苏州大学附属常熟医院药剂科，江苏常熟 215500） 中图分类号 R975；R969.3 文献标志码 A 文章编号 1001-0408（2015）14-1914-04 DOI 10.6039/j.issn. 1001-0408.2015.14.13 摘 要 目的：为临床合理使用质子泵抑制剂（PPIs ）和医药产业政策调整提供参考。方法：采用回顾性方法，对我院2011－2013 年PPIs 的销售金额、用药频度（DDDs ）和日均费用（DDC ）等进行统计分析。结果：PPIs 的销售金额和DDDs 呈快速增长态势，年均 复合增长率为46.47％。口服PPIs 的销售金额和DDDs 占比分别为31.22％、84.25％，注射用PPIs 的销售金额和DDDs 占比分别为 68.78％、15.75％。3年销售金额排前3位的是注射用泮托拉唑、奥美拉唑和兰索拉唑（29.81％、21.36％、13.81％）；3年DDDs 排前 3位的是奥美拉唑、兰索拉唑和雷贝拉唑口服剂（35.00％、28.84％、14.03％）。结论：奥美拉唑和兰索拉唑用量相对较大，但不可忽 视临床存在注射剂过度使用、无指征用药、使用疗程过长和用法用量不合理现象。 关键词 质子泵抑制剂；限定日剂量；用药频度；日均费用；用药分析 Analysis of the Application of Proton Pump Inhibitors in Our Hospital from 2011to 2013 ZHU Ai-guo ，WANG Jian ，ZHANG Gui-fen （Dept. of Pharmacy ，Changshu Hospital Affiliated to Soochow Uni- versity ，Jiangsu Changshu 215500，China ） ABSTRACT OBJECTIVE ：To provide reference for clinical rational use of proton pump inhibitors （PPIs ）and pharmaceutical in- dustry policy adjustment. METHODS ：By retrospective study ，the utilization of PPIs in our hospital during 2011-2013 was ana- lyzed statistically in respects of consumption sum ，DDDs and DDC ，etc. RESULTS ：The consumption sum and DDDs of PPIs in our hospital were increasing rapidly. Compound annual growth rate （CAGR ）of the consumption sum was 46.47％. The proportion of consumption sum and DDDs of oral PPIs were 31.22％ and 84.25％，respectively. The proportion of consumption sum and DDDs of PPIs for injection were 68.78％and 15.75％，respectively. The top 3drugs in the list of consumption sum in 3years were pantoprazole ，omeprazole and Lansoprazole for injection （29.81％，21.36％and 13.81％）. The top 3 drugs in the list of DDDs in 3 years were omeprazole ，lansoprazole and rabeprazole oral agents （35.00％，28.84％，14.03％）. CONCLUSIONS ：The amount of omeprazole and lansoprazole is