激素免疫抑制剂和IFX用于IBD的指南.pdfVIP

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激素免疫抑制剂和IFX用于IBD的指南

GASTROENTEROLOGY 2006;130:935–939 AMERICAN GASTROENTEROLOGICAL ASSOCIATION INSTITUTE American Gastroenterological Association Institute Medical Position Statement on Corticosteroids, Immunomodulators, and Infliximab in Inflammatory Bowel Disease A) or budesonide (Grade B) is effective for distal See CME Quiz on page 932. colonic inflammation. he following recommendations were developed to Moderate to severe IBD. Tassist physicians in the appropriate use of medica- ● Corticosteroids such as prednisone are effective in both tions to treat patients with inflammatory bowel disease patients with CD and patients with UC. (Grade A) (IBD). These recommendations represent the results of many years of research and many collaborative efforts. ● Corticosteroids are not effective for the treatment of The medications reviewed include corticosteroids, aza- patients with perianal fistulas (Grade C). thioprine (AZA), 6-mercaptopurine (6-MP), methotrex- Severe and fulminant IBD. ate, mycophenolate mofetil, cyclosporine, and infliximab. ● Hospitalization for parenteral corticosteroids is in- Corticosteroids dicated for patients failing to respond to oral corti- costeroids or for patients with severe disease with Corticosteroids are potent, rapidly

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