胱抑素C和β2微球蛋白在2型糖尿病早期肾病诊断方面的研究.pdfVIP

The significance of cystatin C and β2 microglobulin in the diagnosis of type 2 early diabetic nephropathy Objective To investigate the serum cystatin C (Cys C), and clinical application of serum β2 microglobulin (β2 - MG) levels in type 2 diabetic nephropathyValue in use. Methods Diabetic patients urinary protein levels is divided into two groups, the quantitative determination of the patients serum Cys C in β2 - MG, creatinine (Cr), urineFactors nitrogen (BUN) concentration and positive rate, and the results with normal healthy individuals (control group). The results of early diabetic nephropathy group, simple diabetes Group of Cys C, β2 - MG level was significantly higher (P 0 05); in patients with diabetic nephropathy group, Cys C and β2 in - MG positive rateMore than 50% in the DM group, Cys C and β2 - MG positive rate higher than the Cr and BUN levels, the difference was statisticallySignificance (P 0 05). With the extension of the course, the condition is aggravated, Cys, C, and β2 - MG abnormal changes more significant (P 0 05). Conclusions SerumCys C blood β2 - MG had a higher detection rate in early diabetic nephropathy, they have a certain application value in the screening of diabetic nephropathy. Key words diabetic nephropathy; cystatin C; β2 microglobulin; early detection 中英文对照 英文缩写 英文全称 中文全称 T2DM Type 2 diabetes 2 型糖尿病 DN Diabetic nephropathy 糖尿病肾病 UAER Urinary protein excretion rate 尿蛋白排泄率 Cys C Cystatin C 胱抑素c β2 － MG Beta 2 microglobulin β2 微球蛋白 BUN Blood urea nitrogen 尿素氮 Cr