厦门大学附属中山医院2005～2012年新发急性髓性白血病初步分析.pdfVIP

·11388 · 中华临床医师杂志( 电子版)2013 年12 月第7 卷第24 期 Chin J Clinicians(Electronic Edition),December 15,2013,Vol.7,No.24 ·临床论著· 厦门大学附属中山医院2005～2012 年新发 急性髓性白血病初步分析 顾龙 肖芸 吕晓楠 叶辉铭 刘祝君 曾骥孟 【摘要】 目的 分析厦门大学附属中山医院近年来急性髓性白血病的发病情况与趋势，从中了解本地 区急性髓性白血病的流行趋势，为制定科学的防治方法提供依据。方法 回顾性分析2005～2012 年厦门大 学附属中山医院就诊的初发急性髓性白血病病例资料，统计分析年龄、性别、亚型及疗效的差异。结果 新 发急性髓性白血病患者的男女比例相当，无差异，25 至59 岁的中青年为高发病人群，其中35 至39 岁年龄 段最高发，75 到79 岁出现老年人发病小高峰；M2 、M3 、M5 是发病人数最多的三个亚型，且在未成 年人、成年人、老年人不同年龄段组的发病比例有显著差异；2005～2012 年新增患者人数具有上升趋 势。结论 2005～2012 年本院新发急性髓性白血病人数呈上升趋势，不同年龄段新发病例疗效差异显著可 能与疾病亚型相关。 【关键词】 白血病，髓样，急性； 治疗结果； 流行病学； 亚型； 疾病控制 Preliminary analysis of newly diagnosed acute myeloid leukemia from 2005 to 2012 in Zhongshan Hospital Xiamen University GU Long, XIAO Yun, LV Xiao-nan, YE Hui-ming, LIU Zhu-jun, TZENG Chi-meng. Translational Medicine Research Center, School of Pharmaceutical Science Xiamen University, Xiamen 361005, China Corresponding author: TZENG Chi-meng, Email: cmtzeng@xmu.edu.cn 【Abstract 】 Objective To explore the morbidity and trend of acute myeloid leukemia of Zhongshan Hospital Xiamen University in recent years, and to provide support for its prevention and intervention. Methods The retrospective analysis of acute myeloid leukemia patient of Zhongshan Hospital Xiamen University from 2005 to 2012 was made to analyze the differences among age, gender, subtype, and curative effect. Results The ratio of newly diagnosed acute myeloid leukemia between male and female was nearly same. The incidence of young and middle aged population between 25 to 59 years old was high. Among them, the highest incidence appeared in people aged 35 to 39. There was a small peak of incidence in old population aged 75 to 79. M2, M3, M5 were the most common subtypes of all patients, and there